Brailski Kh, Dimitrov B
Vutr Boles. 1987;26(2):79-82.
The effect of the new Bulgarian preparation gastralgin was studied in 20 patients with duodenal ulcer. The preparation was given three times daily in the course of 20 days--I bag, 1/2 to 1 hour before meals and in the evening before going to bed. Gastralgin contains in one bag--alginic acid 0.500, sodium alginate 0.500, aluminium hydroxide 0.200, magnesium hydroxide 0.100, calcium carbonate 0.500 and corrigent up to 7g. Favourable effect on the separate symptoms was attained in 50 to 80% after the treatment, epithelialization of the ulcer in 40% and reduction of its size in 25%. No change in gastric secretion was observed. Gastralgin, with its therapeutic effect, is equivalent to the preparations almagel and flatugel and their improved variants. The preparation is well tolerated and gives no adverse effects, hence it is recommended for the treatment of duodenal ulcer.
对20例十二指肠溃疡患者研究了新型保加利亚制剂胃速乐的疗效。该制剂每日服用3次,疗程为20天,每次1袋,于饭前半小时至1小时及晚上睡前服用。每袋胃速乐含藻酸0.500、海藻酸钠0.500、氢氧化铝0.200、氢氧化镁0.100、碳酸钙0.500及矫味剂至7g。治疗后50%至80%的患者各症状有改善,40%的溃疡面实现上皮化,25%的溃疡面缩小。未观察到胃液分泌有变化。胃速乐的治疗效果与胃舒平、胃仙-U及其改进型制剂相当。该制剂耐受性良好,无不良反应,因此推荐用于治疗十二指肠溃疡。