Stip E, Al Mugaddam F, Nauman J, Baki A Abdel, Potvin S
Department of Psychiatry and Behavioral Sciences, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Department of Psychiatry and Addictology, University of Montreal, Montreal, QC, Canada.
Schizophr Res Cogn. 2022 Aug 18;30:100267. doi: 10.1016/j.scog.2022.100267. eCollection 2022 Dec.
A network of early psychosis-specific intervention programs at the University of Montreal in Montreal, Quebec, Canada, conducted a longitudinal naturalistic five-year study at two Urban Early Intervention Services (EIS). In this study, 198 patients were recruited based on inclusion/exclusion criteria and agreed to participate. Our objectives were to assess the subjective cognition complaints of schizophrenic patients assessed by Subjective Scale to Investigate Cognition in Schizophrenia (SSTICS) in their first-episode psychosis (FEP) in relation to their general characteristics. We also wanted to assess whether there are sex-based differences in the subjective cognitive complaints, as well as differences in cognitive complaints among patients who use alcohol in comparison to those who are abstainers. Additionally, we wanted to monitor the changes in the subjective complaints progress for a period of five years follow-up. Our findings showed that although women expressed more cognitive complaints than men [mean (SD) SSTICS, 28.2 (13.7) for women and 24.7 (13.2) for men], this difference was not statistically significant ( = -0.190, 95 % CI, -0. 435 to 0. 097). We also found that abstainers complained more about their cognition than alcohol consumers [mean (SD) SSTICS, 27.9 (13.4) for abstainers and 23.7 (12.9) for consumers], a difference which was statistically significant ( = -0.166, 95 % CI, -0. 307 to -0.014). Our findings showed a drop in the average score of SSTICS through study follow-up time among FEP patients. In conclusion, we suggest that if we want to set up a good cognitive remediation program, it is useful to start with the patients' demands. This demand can follow the patients' complaints. Further investigations are needed in order to propose different approaches between alcohol users and abstinent patients concerning responding to their cognitive complaints.
加拿大魁北克省蒙特利尔市蒙特利尔大学的一个早期精神病特异性干预项目网络,在两个城市早期干预服务机构(EIS)开展了一项为期五年的纵向自然主义研究。在这项研究中,根据纳入/排除标准招募了198名患者并同意参与。我们的目标是评估精神分裂症患者在首次发作精神病(FEP)时通过精神分裂症认知调查主观量表(SSTICS)评估的主观认知主诉与其一般特征的关系。我们还想评估主观认知主诉中是否存在基于性别的差异,以及与戒酒者相比,饮酒患者在认知主诉方面的差异。此外,我们想在五年的随访期内监测主观主诉进展的变化。我们的研究结果表明,虽然女性比男性表达了更多的认知主诉[平均(标准差)SSTICS,女性为28.2(13.7),男性为24.7(13.2)],但这种差异无统计学意义(= -0.190,95%可信区间,-0.435至0.097)。我们还发现,戒酒者比饮酒者对自己的认知抱怨更多[平均(标准差)SSTICS,戒酒者为27.9(13.4),饮酒者为23.7(12.9)],这一差异具有统计学意义(= -0.166,95%可信区间,-0.307至-0.014)。我们的研究结果显示,在FEP患者的研究随访期间,SSTICS的平均得分有所下降。总之,我们建议,如果我们想建立一个良好的认知康复项目,从患者需求入手是有用的。这种需求可以遵循患者的抱怨。为了针对饮酒者和戒酒患者在应对其认知抱怨方面提出不同方法,还需要进一步研究。