Secretaria de Estado da Saúde do Espírito Santo, Subsecretaria de Estado de Vigilância em Saúde, Vitória, ES, Brasil.
Universidade Federal do Espírito Santo, Departamento de Medicina Social, Vitória, ES, Brasil.
Epidemiol Serv Saude. 2022 Aug 29;31(2):e2022112. doi: 10.1590/S1679-49742022000200023. eCollection 2022.
To analyze SARS-CoV-2 seroprevalence and association of sociodemographic and clinical aspects in the state of Espírito Santo, Brazil.
This was a serial cross-sectional study carried out in four phases, using households as the unit of analysis, from May to June 2020. Eleven municipalities were surveyed, with a sample of 4,500 households in each phase.
Prevalence ranged from 2.1% (95%CI 1.7;2.5) on May 10 (first phase) to 9.6% (95%CI 8.8;10.4) on June 21 (fourth phase). In the Greater Vitória Metropolitan Region, the prevalence were 2.7% (95%CI 2.2;3.3) in the first phase, and 11.5% (95%CI 10.5;12.6) in the fourth phase; in the interior region of the state, prevalence ranged from 0.4% (95%CI 0.1;0.9) to 4.4% (95%CI 3.2;5.5) between the two phases.
The increase in SARS-CoV-2 seroprevalence found in the fourth phase highlighted the high transmission of the virus, information that can support management of the pandemic.
分析巴西圣埃斯皮里图州 SARS-CoV-2 的血清流行率及与社会人口学和临床方面的关联。
这是一项于 2020 年 5 月至 6 月期间分四个阶段进行的连续横断面研究，以家庭为分析单位。调查了 11 个城市，每个阶段的样本量为 4500 户。
5 月 10 日（第一阶段）的流行率为 2.1%（95%CI 1.7；2.5），6 月 21 日（第四阶段）为 9.6%（95%CI 8.8；10.4）。在大维多利亚大都市区，第一阶段的流行率为 2.7%（95%CI 2.2；3.3），第四阶段为 11.5%（95%CI 10.5；12.6）；在该州内陆地区，两阶段的流行率范围为 0.4%（95%CI 0.1；0.9）至 4.4%（95%CI 3.2；5.5）。
第四阶段 SARS-CoV-2 血清阳性率的增加强调了病毒的高传播性，这一信息可以为大流行的管理提供支持。
