Ibn Rochd University Hospital, Hassan II University, Faculty of Medicine and Pharmacy, Medico-legal Institute, Casablanca, Morocco.
Ibn Rochd University Hospital, Hassan II University, Faculty of Medicine and Pharmacy, Histopathology Department, Casablanca, Morocco.
Malays J Pathol. 2022 Aug;44(2):277-283.
Arrhythmogenic right ventricular cardiomyopathy is an underdiagnosed myocardial disease which commonly presents with sudden cardiac death in young people. It is considered as a challenge for forensic pathologist due to its pathological changes. Here, we presented three cases of postmortem diagnosis of arrhythmogenic right ventricular cardiomyopathy with involvement of other subtypes.
Here, we report autopsy cases of sudden cardiac death as the first clinical manifestation observed in three patients with different ages and with no medical history, nor previous family history of sudden death or heart diseases. The postmortem investigations were performed and the diagnosis of arrhythmogenic cardiomyopathy with three expression forms was later confirmed by histopathological examination, this latter showed fibroadipose tissue infiltrations of the myocardium. The diagnosis of arrhythmogenic cardiomyopathy was discussed with review through the literature.
We presented special characteristic and histopathology features of arrhythmogenic cardiomyopathy cases, discovered in our usual forensic practice. This may be helpful for forensic pathologists to make a reliable diagnosis even in the absence of clinical history.
致心律失常性右室心肌病是一种诊断不足的心肌疾病，常导致年轻人发生心源性猝死。由于其病理变化，它对法医病理学家来说是一个挑战。在这里，我们介绍了三例涉及其他亚型的致心律失常性右室心肌病的死后诊断病例。
在这里，我们报告了三例尸检病例，这些病例均以不同年龄的患者为首发临床表现，无既往病史，也无猝死或心脏病的家族史。进行了尸检调查，随后通过组织病理学检查证实了致心律失常性心肌病的三种表现形式的诊断，后者显示心肌纤维脂肪组织浸润。通过文献复习讨论了致心律失常性心肌病的诊断。
我们介绍了在我们通常的法医实践中发现的致心律失常性心肌病病例的特殊特征和组织病理学特征。即使没有临床病史，这也可能有助于法医病理学家做出可靠的诊断。
