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[子宫内膜中雌二醇受体的测定——对功能性不育诊断的贡献]

[Determination of estradiol receptors in the endometrium--a contribution to the diagnosis of functional sterility].

作者信息

Seliger E, Seifert B, Rothe K, Nickel I, Bettzieche H

出版信息

Zentralbl Gynakol. 1987;109(8):493-500.

PMID:3604493
Abstract

In 86 cases of female infertility an endometrial biopsy was performed. The received tissues were examined by histological methods and the binding of estradiol on the specific cytoplasmic receptor was studied. Serum levels of estradiol and progesterone were estimated at the same day.--The estradiol receptor levels from ovulatory cycles are directly dependent on the histological dated phase of the menstrual cycle. The level was highest in late proliferative phase and declines during the secretory phase.--Luteal phase deficiency and other luteal phase defects are connected with a decrease of estrogen receptor concentrations in secretory endometrium.

摘要

对86例女性不孕症患者进行了子宫内膜活检。对所获取的组织进行组织学检查,并研究雌二醇与特异性细胞质受体的结合情况。同日测定血清雌二醇和孕酮水平。——排卵周期的雌二醇受体水平直接取决于月经周期的组织学分期。该水平在增殖期晚期最高,在分泌期下降。——黄体期缺陷及其他黄体期异常与分泌期子宫内膜中雌激素受体浓度降低有关。

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Zentralbl Gynakol. 1987;109(8):493-500.
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