Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, 430030, Wuhan, People's Republic of China.
Public Security Bureau of Gutian, No. 16 West Binhe Road, Chengdong Street, 352200, Gutian, People's Republic of China.
Forensic Sci Med Pathol. 2022 Dec;18(4):497-502. doi: 10.1007/s12024-022-00517-x. Epub 2022 Sep 1.
Bungarus multicinctus (B. multicinctus) is one of the top ten venomous snakes in China, ranking first in lethality at 26.9-33.3%. However, to our knowledge, no forensic autopsy-related cases of death from B. multicinctus bite poisoning have been reported. There are surprisingly few reported cases of death from poisoning by other species of neurotoxic snakes. Neurotoxic snake venom is often highly toxic, and death can quickly occur when bitten in the wild if victims are not taken to a doctor in time. We presented a case of an adult female in Fujian Province of China who was bitten by a poisonous snake while digging for bamboo shoots in the mountains and died from the bite of B. multicinctus confirmed by enzyme-linked immunosorbent assays (ELISA) results. The autopsy's results, histopathological findings, and ELISA results reported here can be helpful for future forensic practice in B. multicinctus venom poisoning; we also briefly review the pathological changes of neurotoxin poisoning, which may be useful in other types of neurotoxin snake venom poisoning.
金环蛇(B. multicinctus)是中国十大毒蛇之一,致死率高达 26.9-33.3%,排名第一。然而,据我们所知,目前还没有金环蛇咬伤中毒导致法医解剖相关的死亡案例报告。其他神经毒素毒蛇中毒导致死亡的报告案例则少之又少。神经毒素毒蛇毒液通常毒性很强,如果在野外被咬伤的患者未能及时就医,很快就会死亡。我们报告了一起中国福建省的成年女性案例,该女性在山上挖竹笋时被毒蛇咬伤,经酶联免疫吸附试验(ELISA)结果证实为金环蛇咬伤中毒导致死亡。本案例的尸检结果、组织病理学发现和 ELISA 结果可为今后金环蛇毒液中毒的法医学实践提供帮助;我们还简要回顾了神经毒素中毒的病理变化,这可能对其他类型的神经毒素毒蛇毒液中毒也具有一定的参考价值。