Department of Sports Training, Nanjing Sport Institute, Nanjing, China.
Department of Chaohu Clinical Medicine, Anhui Medical University, Hefei, China.
Front Public Health. 2022 Aug 15;10:923161. doi: 10.3389/fpubh.2022.923161. eCollection 2022.
Gestational hypertension (GH) is a common disease that seriously threatens the safety and health of pregnant women and their newborns. Physical exercise (PE) is widely recognized as a health maintenance method and it has numerous benefits. Studies on the association between PE and the risk of GH in obese and overweight pregnant women have generated controversial findings. This updated meta-analysis was performed to reassess the effects of PE on GH.
The articles from inception to April 2022, presenting studies investigating exercise intervention and pregnancy outcomes were explored across several online databases. Heterogeneity among the included studies was estimated and tested by Q test and statistic. Risk ratios (RRs) and 95% confidence intervals (CI) were calculated through either random-effect or fixed-effect models. Subgroup analyses, sensitivity analyses, and publication bias diagnoses were also conducted.
Twelve with 1,649 subjects were included. PE was associated with a reduced risk of GH in obese and overweight pregnant women (Pooled RR = 0.58, 95% CI = 0.42-0.81, = 0.001; = 24.3%). Subgroup analysis found significant trends amongst Eastern countries (RR = 0.59, 95% CI = 0.36-0.96, = ). Sensitivity analysis suggested the results were stable. No publication bias was detected based on Begg's test and Egger's test.
PE was associated with reduced risk of GH in obese and overweight pregnant women, especially in Eastern countries. More well-designed studies are still needed to further elaborate on these associations.
CRD42022326183.
妊娠期高血压（GH）是一种常见疾病，严重威胁着孕妇及其新生儿的安全和健康。体育锻炼（PE）被广泛认为是一种保持健康的方法，具有许多益处。关于 PE 与肥胖和超重孕妇 GH 风险之间关系的研究得出了相互矛盾的结果。本更新的荟萃分析旨在重新评估 PE 对 GH 的影响。
从创建到 2022 年 4 月，检索了多个在线数据库中关于运动干预与妊娠结局的研究文章。通过 Q 检验和 I ² 检验评估纳入研究的异质性。通过随机效应或固定效应模型计算风险比（RR）和 95%置信区间（CI）。还进行了亚组分析、敏感性分析和发表偏倚诊断。
纳入了 12 项研究，共 1649 名受试者。PE 与肥胖和超重孕妇 GH 的风险降低相关（汇总 RR = 0.58，95%CI = 0.42-0.81， = 0.001； I ² = 24.3%）。亚组分析发现东亚国家存在显著趋势（RR = 0.59，95%CI = 0.36-0.96， = ）。敏感性分析表明结果稳定。基于 Begg 检验和 Egger 检验未发现发表偏倚。
PE 与肥胖和超重孕妇 GH 的风险降低相关，尤其是在东亚国家。仍需要更多设计良好的研究来进一步阐明这些关联。
CRD42022326183。
