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一种可行的多模态光声成像方法,用于评估炎症性关节炎的临床症状。

A Feasible Multimodal Photoacoustic Imaging Approach for Evaluating the Clinical Symptoms of Inflammatory Arthritis.

机构信息

Department of Electronics and Communication Engineering, Sathyabama Institute of Science and Technology, Chennai, 600119 Tamil Nadu, India.

Department of Electronics and Communication Engineering, Saveetha School of Engineering, SIMATS, Chennai, 602 105 Tamil Nadu, India.

出版信息

Biomed Res Int. 2022 Aug 21;2022:7358575. doi: 10.1155/2022/7358575. eCollection 2022.

DOI:10.1155/2022/7358575
PMID:36046441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9420593/
Abstract

Numerous traditional medical imaging methods, including computed tomography with X-rays, positron emission tomography (PET), and magnetic resonance imaging (MRI), are utilized frequently in medical settings to screen for illnesses, diagnose patients, and track the effectiveness of treatments. When examining bone protrusions, CT is preferred over MRI for scanning connective tissue. Although the picture quality of PET is inferior to that of CT and MR, it is outstanding for detecting the molecular markers and metabolic functions of illnesses. To give high-resolution structural pictures and improved ailment sensitivity and specificity within another image, multimodal data and substantial therapeutic influence on advanced diagnostics and therapeutics have been used. The goal was to evaluate the clinical significance of multimodal photoacoustic/ultrasound (PA/US) articular imaging scoring, a cutting-edge image technique that may show the microvessels and oxygen levels of rheumatoid arthritis-related inflamed joints (RA). The PA/US imaging technology analyzed seven tiny joints. The PA and power Doppler (PD) impulses were semiquantified using a 0-3 grading scale, and the averages of the PA and PD scores for the seven joints are computed. Three PA+SO types were found determined by the relative oxygen levels (SO) measurements of the affected joints. Researchers evaluated the relationships between the disease activity ratings and the PA/US imaging ratings. The PA scores and medical ratings that reflect the extent of the pain have strong relationships with each other, as do the PA+SO combinations. PA may be clinically useful in assessing RA. Thus, the research evaluated the clinical symptoms of inflammatory arthritis using a multimodal photoacoustic image process.

摘要

许多传统的医学成像方法,包括 X 射线计算机断层扫描、正电子发射断层扫描(PET)和磁共振成像(MRI),经常被用于医疗环境中,以筛查疾病、诊断患者和跟踪治疗效果。在检查骨突起时,CT 比 MRI 更适合扫描结缔组织。虽然 PET 的图像质量不如 CT 和 MR,但它在检测疾病的分子标志物和代谢功能方面表现出色。为了在另一幅图像中提供高分辨率的结构图像,并提高疾病的敏感性和特异性,多模态数据和对先进诊断和治疗的大量治疗影响已经被使用。目的是评估多模态光声/超声(PA/US)关节成像评分的临床意义,这是一种先进的图像技术,可以显示类风湿关节炎相关炎症关节(RA)的微血管和氧气水平。PA/US 成像技术分析了七个小关节。使用 0-3 分级量表对 PA 和功率多普勒(PD)脉冲进行半定量分析,并计算七个关节的 PA 和 PD 评分的平均值。根据受影响关节的相对氧水平(SO)测量结果,确定了三种 PA+SO 类型。研究人员评估了疾病活动评分与 PA/US 成像评分之间的关系。反映疼痛程度的 PA 评分和医学评分之间存在很强的相关性,PA+SO 组合也是如此。PA 可能在评估 RA 方面具有临床应用价值。因此,该研究使用多模态光声图像处理评估了炎症性关节炎的临床症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/c3f8811a7c4f/BMRI2022-7358575.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/9886f89e32a3/BMRI2022-7358575.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/b9552e82c999/BMRI2022-7358575.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/16af2fe6e650/BMRI2022-7358575.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/76cdd8385fca/BMRI2022-7358575.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/c3f8811a7c4f/BMRI2022-7358575.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/9886f89e32a3/BMRI2022-7358575.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/b9552e82c999/BMRI2022-7358575.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/16af2fe6e650/BMRI2022-7358575.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/76cdd8385fca/BMRI2022-7358575.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df5/9420593/c3f8811a7c4f/BMRI2022-7358575.005.jpg

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