冷冻活检与19G穿刺针及22G穿刺针联合超声支气管镜引导针吸活检术的比较

Cryo-Biopsy versus 19G needle versus 22G needle with EBUS-TBNA endoscopy.

作者信息

Oikonomidou Rena, Petridis Dimitris, Kosmidis Christoforos, Sapalidis Konstantinos, Hohenforst-Schmidt Wolfgang, Christakidis Vagelis, Petanidis Savas, Mathaios Dimitris, Perdikouri Eleni Isidora, Baka Sofia, Tolis Christos, Vagionas Anastasios, Zaric Bojan, Ioannidis Aris, Anemoulis Marios, Porpodis Konstantinos, Papadopoulos Vasileios, Zarogoulidis Paul

机构信息

Health Center of Evosmos, Thessaloniki, Greece.

Department of Food Technology, School of Food Technology and Nutrition, Alexander Technological Educational Institute, Thessaloniki, Greece.

出版信息

J Cancer. 2022 Aug 8;13(10):3084-3090. doi: 10.7150/jca.75589. eCollection 2022.

We have been using cryo-biopsy for endobronchial lesions for lung cancer diagnosis and debulking. Cryo-biopsy is also known to be an excellent tool for diagnosis of lung interstitial disease. Recently cryo-biopsy with the 1.1mm probe was used for lymphnode biopsy. 311 patients participated with lymphadenopathy and at least one lung lesion. The following tools were used for diagnosis; 22G Mediglobe Sonotip, 22G Medigolbe, 21G Olympus, 19G Olympus and 1.1mm cryo probe ERBE CRYO 2 system (3 seconds froze). A PENTAX Convex-probe EBUS was used for biopsy guidance. Cell-blocks slices had a higher number in the 19G needle group (19G> Cryo Probe>22G Mediglobe Sonotip >21G Olympus >22G Mediglobe). Cryo biopsy of the lymphnodes is safe with the 1.1mm cryo probe. Further studies are needed in order to evaluate new probes and the technique specifications.

我们一直在使用冷冻活检来诊断和减瘤支气管内肺癌病变。冷冻活检也是诊断肺间质疾病的一种优秀工具。最近，使用1.1毫米探头的冷冻活检用于淋巴结活检。311例有淋巴结肿大和至少一个肺部病变的患者参与了研究。使用了以下工具进行诊断：22G Mediglobe Sonotip、22G Medigolbe、21G奥林巴斯、19G奥林巴斯和1.1毫米冷冻探头ERBE CRYO 2系统（冷冻3秒）。使用宾得凸探头EBUS进行活检引导。19G针组的细胞块切片数量更多（19G>冷冻探头>22G Mediglobe Sonotip>21G奥林巴斯>22G Mediglobe）。使用1.1毫米冷冻探头对淋巴结进行冷冻活检是安全的。为了评估新探头和技术规格，还需要进一步研究。