Zhu Yin, Shen Hui, Lerner Andrew D, Li Qin, Chen Si, Zhou Lingxiao, Zhou Jiaqi, Xia Yang, Wang Kopen
Department of Respiratory and Critical Care Medicine, Key Laboratory of Respiratory Disease of Zhejiang Province, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, China.
Cancer Center, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Chin Med J Pulm Crit Care Med. 2024 Jul 31;2(3):162-170. doi: 10.1016/j.pccm.2024.05.002. eCollection 2024 Sep.
Transbronchial needle aspiration (TBNA) is a commonly used sampling approach in the diagnosis of hilar and mediastinal lymphadenopathy as well as peripheral lesions. As a very important tool, the continued innovation of TBNA needles is a vital driving force for the development of the technique. Although TBNA plays an important role in interventional pulmonology, there are no clear standards guiding operators to choose an appropriate needle for their operation. In recent decades, with the advent of endobronchial ultrasound-guided TBNA (EBUS-TBNA), the real-time visualization of TBNA has been enabled. These modern TBNA needles, such as ViziShot2, FLEX 19G, Acquire FNB, and EchoTip ProCore, have made significant progress in specimen collection, convenience, and safety, though still remain grounded in the basic premise and initial upgrades to the original conventional TBNA (cTBNA) needles. This review introduced the developmental history of WANG cTBNA needles, and summarized the lessons of success and failure and the enlightenments for currently used EBUS- and other emerging TBNA needles, aiming to provide a significant reference for pulmonologists who lived through the cTBNA era and for junior physicians who start working in the EBUS-TBNA era. Despite its long history, TBNA is still playing significant roles in the diagnosis of pulmonary diseases. A deeper understanding from the historical perspectives would facilitate continued innovations in the field of TBNA and beyond.
经支气管针吸活检术（TBNA）是诊断肺门和纵隔淋巴结病变以及周围性病变常用的采样方法。作为一项非常重要的工具，TBNA针的不断创新是该技术发展的重要驱动力。尽管TBNA在介入肺病学中发挥着重要作用，但目前尚无明确的标准指导操作者选择合适的针具进行操作。近几十年来，随着支气管内超声引导下经支气管针吸活检术（EBUS-TBNA）的出现，实现了TBNA的实时可视化。这些现代TBNA针，如ViziShot2、FLEX 19G、Acquire FNB和EchoTip ProCore，在标本采集、便利性和安全性方面取得了显著进展，尽管它们仍然基于原始传统TBNA（cTBNA）针的基本前提和初步升级。本文回顾了王氏cTBNA针的发展历程，总结了其成败经验以及对当前使用的EBUS和其他新兴TBNA针的启示，旨在为经历过cTBNA时代的肺病学家以及在EBUS-TBNA时代开始工作的年轻医生提供重要参考。尽管TBNA历史悠久，但它在肺部疾病诊断中仍发挥着重要作用。从历史角度进行更深入的理解将有助于推动TBNA及相关领域的持续创新。
