Liu Ming-Xi, Zhang Ning, Gao Qi, Xu Zi-Hang, Wang Bing, Zhu Guo-Qin, Zou Chun-Pu
School of Basic Medical Science, Application and Research Center of Classical Prescription, Science and Technology Experiment Center, Shanghai University of Traditional Chinese Medicine Shanghai 201203, China.
Shanghai Xingling Technology Pharmaceutical Co., Ltd. Shanghai 201203, China.
Zhongguo Zhong Yao Za Zhi. 2022 Aug;47(15):4025-4032. doi: 10.19540/j.cnki.cjcmm.20210804.301.
The classical famous prescription Dajianzhong Decoction is recorded in Synopsis of the Golden Chamber written by Zhang Zhongjing in the Eastern Han Dynasty. It has a long history and definite clinical effects, while this prescription has not been manufactured into Chinese patent medicine preparation. We collected many ancient books of traditional Chinese medicine(TCM) by using the method of bibliometrics and got 211 valid data terms which involved 67 ancient books. The history, main treated syndromes, formulation principle, origins and processiong of medicinal materials, and decoction method of Dajianzhong Decoction were analyzed. Despite the different views of various generations of medical experts toward the composition of this prescription, the compatibility ratio of Ginseng Radix et Rhizoma to Zingiberis Rhizoma Recens is constant. Furthermore, we explored the origins of synonyms of Dajianzhong Decoction. On the basis of this study, we hope to gain an insight into the research and development of the compound preparations of Dajianzhong Decoction and provide reference for the heritage and innovation of other classical prescriptions.
经典名方大建中汤载于东汉张仲景所著的《金匮要略》。其历史悠久，临床疗效确切，但该方尚未制成中成药制剂。我们运用文献计量学方法收集了多部中医古籍，得到211个有效数据词条，涉及67部古籍。对大建中汤的历史、主治证候、组方原理、药材来源与炮制以及煎服方法进行了分析。尽管历代医家对该方的组成有不同看法，但人参与生姜的配伍比例是恒定的。此外，我们还探究了大建中汤异名的由来。在此研究基础上，希望能深入了解大建中汤复方制剂的研发情况，为其他经典方剂的传承与创新提供参考。
