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辣椒素预处理对大鼠烫伤炎症反应的影响。

Effects of capsaicin pretreatment on the inflammatory response to scalding injury in the rat.

作者信息

Haegerstrand A, Dalsgaard C J, Jonsson C E

出版信息

Acta Physiol Scand. 1987 Jun;130(2):345-8. doi: 10.1111/j.1748-1716.1987.tb08146.x.

Abstract

The oedema formation after scalding injury to the rat paw was studied by means of the Evans blue exudation technique. An early and a delayed oedema formation were demonstrated after severe and light scalding, respectively. It was shown that the delayed, but not the early, form was reduced by capsaicin pretreatment, suggesting an involvement of chemosensitive primary sensory neurons in this reaction.

摘要

采用伊文思蓝渗出技术研究了大鼠爪烫伤后的水肿形成。重度烫伤和轻度烫伤后分别出现早期水肿形成和延迟性水肿形成。结果表明,辣椒素预处理可减轻延迟性水肿形成,但不能减轻早期水肿形成,提示化学敏感的初级感觉神经元参与了该反应。

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