Sestin P, Innocenti A
Allergol Immunopathol (Madr). 1987 Jan-Feb;15(1):25-8.
Clinical characteristics of allergic asthma due to inhalation of insect antigens have been investigated very little. We describe two patients presenting with dyspnoea and wheezing several hours after exposure to larvae of Calliphora erythrocephala used as fishing bait. Both patients had a positive intradermal skin test and a high level of circulating IgE to the specific allergen. Bronchial challenge test with the whole larvae resulted in an isolated late response in one case, and in a dual response in the other, which were prevented by premedication with DSCG or beclometazone. The occurrence of late asthmatic reactions may render it difficult for the identification of insect antigens as the causal agent of extrinsic allergic asthma.
吸入昆虫抗原所致过敏性哮喘的临床特征鲜有研究。我们描述了两名患者，他们在接触用作鱼饵的红头丽蝇幼虫数小时后出现呼吸困难和喘息。两名患者的皮内皮肤试验均呈阳性，且针对特定过敏原的循环IgE水平较高。用完整幼虫进行支气管激发试验，一例出现孤立的迟发反应，另一例出现双重反应，而预先使用色甘酸钠或倍氯米松可预防这些反应。迟发性哮喘反应的发生可能使将昆虫抗原鉴定为外源性过敏性哮喘的病因变得困难。
