Su Yan-Qian, Liu Zhao-Yang, Wei Guo, Zhang Chun-Min
Department of Dermato-venereology, The Second Hospital of Shandong University, Jinan 250012, Shandong Province, China.
World J Clin Cases. 2022 Jul 16;10(20):7147-7152. doi: 10.12998/wjcc.v10.i20.7147.
Primary cutaneous amyloidosis (PCA) is a chronic metabolic skin disease that has a detrimental impact on physical and mental health. It appears as mossy papules and severe itching, which is long-term and recurrent. Traditional treatments are unsatisfactory, especially for refractory cases. Fire needle therapy, which is widely used in China, has shown good clinical efficacy, as well as advantages concerning safety and cost. Clinical reports about fire needle treatment of this disease are few at present.
We report two older men who had developed maculopapules with itchiness on the trunk and arms for more than 10-15 years. Due to the dermatopathological findings, PCA was our primary consideration. They received topical halometasone cream and pretreatment with fire needle for 8-16 wk. Both patients showed significant improvement of lesions. Neither patient had recurrence with a minimum of 2 years of follow-up.
Topical halometasone cream and pretreatment with fire needle could be a fast, safe, and economic treatment for PCA.
原发性皮肤淀粉样变（PCA）是一种慢性代谢性皮肤病，对身心健康有不利影响。其表现为苔藓样丘疹和严重瘙痒，且长期反复发作。传统治疗效果不佳，尤其是对于难治性病例。在中国广泛应用的火针疗法已显示出良好的临床疗效，以及在安全性和成本方面的优势。目前关于火针治疗该病的临床报道较少。
我们报告两名老年男性，他们在躯干和手臂出现斑丘疹伴瘙痒超过10 - 15年。根据皮肤病理检查结果，PCA是我们的首要考虑诊断。他们接受了外用卤米松乳膏治疗，并进行了8 - 16周的火针预处理。两名患者的皮损均有显著改善。在至少2年的随访中，两名患者均未复发。
外用卤米松乳膏联合火针预处理可能是一种治疗PCA的快速、安全且经济的方法。
