Mansour Asem, Qandeel Monther, Abdel-Razeq Hikmat, Abu Ali Hussain Ali
Cancer Imaging. 2014 May 7;14(1):22. doi: 10.1186/1470-7330-14-22.
We aimed to characterize specific MRI findings seen in immune competent patients with intracranial primary CNS lymphoma (PCNSL) and to determine their value in the management of such patients. Pre-treatment MRI examinations of 21 immunocompetent patients with biopsy-proven PCNSL were retrospectively evaluated. T1 and T2 signal characteristics as well as contrast enhancement features are described in all patients. Diffusion, perfusion and proton-MR-spectroscopy features are described in a subset of these patients. In the proper clinical and radiologic setting, suggesting the diagnosis of PCNSL can help institute proper treatment in a timely fashion and avoid unnecessary attempts at surgical resection and the associated morbidity.
我们旨在描述免疫功能正常的颅内原发性中枢神经系统淋巴瘤（PCNSL）患者的特定MRI表现，并确定其在这类患者管理中的价值。对21例经活检证实为PCNSL的免疫功能正常患者的治疗前MRI检查进行了回顾性评估。描述了所有患者的T1和T2信号特征以及对比增强特征。在这些患者的一个子集中描述了扩散、灌注和质子磁共振波谱特征。在适当的临床和放射学背景下，提示PCNSL的诊断有助于及时进行适当的治疗，并避免不必要的手术切除尝试及相关并发症。
