以严重发热伴血小板减少综合征病毒感染为病因的儿童不明原因发热：1例报告
Infection of Severe Fever with Thrombocytopenia Syndrome Virus as a Cause of a Child's Fever of Unknown Origin: A Case Report.
作者信息
Zhang Yin, Huang Ying, Xu Yuanhong
机构信息
Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
出版信息
Infect Drug Resist. 2022 Aug 26;15:4871-4875. doi: 10.2147/IDR.S378558. eCollection 2022.
BACKGROUND
Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne disease resulted from SFTSV. It is found in Japan, South Korea, Central, and Eastern China. With the increasing prevalence of SFTS and the rapid spread of the SFTS virus (SFTSV) vector, it is obvious that this virus has pandemic potential and poses an imminent public health concern.
CASE PRESENTATION
We depict SFTS in a child from Anhui Province and conduct a review of all reported pediatric cases in China, which is an endemic area for SFTS. From 2011 to 2021, ten SFTS pediatric cases confirmed by RT-PCR were reported, with no child dying. Although SFTS cases in adolescents and children are uncommon, the reported literature showed that clinical symptoms in adolescents and children were milder than in adults.
CONCLUSION
To better understand this emerging disease, we described the clinical and epidemiological attributes of SFTS. We suggest that the possibility of SFTSV infection in children with seasonal and virus-related acute febrile diseases should be considered in major endemic areas.
背景
发热伴血小板减少综合征（SFTS）是一种由SFTS病毒引起的蜱传疾病。在日本、韩国以及中国中部和东部地区均有发现。随着SFTS患病率的上升以及SFTS病毒（SFTSV）传播媒介的迅速扩散，显然这种病毒具有大流行的潜力，并构成迫在眉睫的公共卫生问题。
病例报告
我们描述了一名来自安徽省儿童的SFTS病例，并对中国这个SFTS流行地区所有已报告的儿科病例进行了回顾。2011年至2021年期间，共报告了10例经逆转录聚合酶链反应（RT-PCR）确诊的SFTS儿科病例，无儿童死亡。尽管青少年和儿童中的SFTS病例并不常见，但已发表的文献表明，青少年和儿童的临床症状比成人轻。
结论
为了更好地了解这种新发疾病，我们描述了SFTS的临床和流行病学特征。我们建议，在主要流行地区，对于患有季节性和病毒相关急性发热疾病的儿童，应考虑SFTSV感染的可能性。
Zotero 插件