Fadlallah Mahdi M, Kharroubi Darine M, Zeineddine Zeinab, Salman Sarah M
Department of Laboratory Medicine, Al-Zahraa Hospital University Medical Center, Beirut, LBN.
Department of Laboratory Medicine, Lebanese University, Faculty of Medical Sciences, Beirut, LBN.
Cureus. 2022 Jul 28;14(7):e27426. doi: 10.7759/cureus.27426. eCollection 2022 Jul.
is a rare non-fermenting gram-negative pathogen that can cause opportunistic infections in humans. Most infections are nosocomial and acquired through contaminated devices such as ventilators, endotracheal tubes, and indwelling catheters. An increasing number of infections have been reported in recent years after the first reported case of ventilator-associated pneumonia in 1993. Blood, lung, ocular, and peritoneal infections, among others, have been reported. The high rate of intrinsic resistance to broad-spectrum antibiotics is a matter of concern since there are no standard guidelines for the management and treatment of this infection. Here, we present the case of a 94-year-old female who was admitted and intubated after a cerebral vascular accident. During her stay, she developed a fever. The deep tracheal aspirate culture was positive for gram-negative bacilli with smooth, circular, and yellow-pigmented colonies that were later identified as . Antimicrobial susceptibility tests done with VITEK 2 and by the Kirby-Bauer disc diffusion method showed susceptibility to ciprofloxacin, minocycline, and trimethoprim-sulfamethoxazole and resistance to all other tested antimicrobials. The infection was successfully treated with ciprofloxacin antibiotic. To the best of our knowledge, this is the first reported case of infection in Lebanon.
是一种罕见的非发酵革兰氏阴性病原体,可导致人类机会性感染。大多数感染是医院获得性的,通过诸如呼吸机、气管内导管和留置导管等受污染设备传播。自1993年首次报告呼吸机相关性肺炎病例以来,近年来报告的感染病例不断增加。还报告了血液、肺部、眼部和腹膜感染等情况。由于对于这种感染的管理和治疗没有标准指南,其对广谱抗生素的固有耐药率较高令人担忧。在此,我们报告一例94岁女性病例,该患者因脑血管意外入院并插管。住院期间,她出现发热。深部气管吸出物培养显示革兰氏阴性杆菌呈光滑、圆形、黄色色素菌落阳性,后来鉴定为 。用VITEK 2和Kirby-Bauer纸片扩散法进行的药敏试验显示对环丙沙星、米诺环素和甲氧苄啶-磺胺甲恶唑敏感,对所有其他测试抗菌药物耐药。该感染用环丙沙星抗生素成功治疗。据我们所知,这是黎巴嫩首次报告的 感染病例。