Mehta Rishika, Pathak Ashish
Department of Pediatrics, RD Gardi Medical College, Ujjain 456006, India.
Department of Women and Children's Health, International Maternal and Child Health Unit, Uppsala University, SE-751 85 Uppsala, Sweden.
Antibiotics (Basel). 2018 Dec 14;7(4):109. doi: 10.3390/antibiotics7040109.
Antibiotic-resistant pathogens and nosocomial infections constitute common and serious problems for neonates admitted to neonatal intensive care units worldwide. is a non-lactose-fermenting, gram-negative, health care-associated pathogen (HCAP). It is ubiquitous and intrinsically resistant to several antibiotics. Despite its low virulence, has been widely reported to cause life-threatening infections. Patients on chronic immunosuppressant drugs, harboring invasive devices and indwelling catheters become the nidus for . Typically, causes major health care-associated infections such as pneumonia, empyema, pyelonephritis, cystitis, peritonitis, meningitis, and bacteremia in patients harboring central venous catheters. Management of infection in neonates is not adequately documented owing to underreporting, particularly in India. Because of its multidrug resistance and the scant availability of data from the literature, the effective empirical treatment of is challenging. We present an uncommon case of bacteremia caused by in a preterm newborn baby with moderate respiratory distress syndrome who was successfully treated. We also provide a review of infections in the neonatal age group. Henceforth, in neonates receiving treatments involving invasive equipment use and long-term antibiotic therapy, multidrug resistant should be considered an HCAP.
抗生素耐药病原体和医院感染是全球新生儿重症监护病房收治的新生儿面临的常见且严重的问题。[病原体名称]是一种非乳糖发酵、革兰氏阴性、与医疗保健相关的病原体（HCAP）。它无处不在，并且对多种抗生素具有内在抗性。尽管其毒力较低，但[病原体名称]已被广泛报道可引起危及生命的感染。使用慢性免疫抑制药物、携带侵入性装置和留置导管的患者成为[病原体名称]的滋生地。通常，[病原体名称]会在携带中心静脉导管的患者中引起主要的与医疗保健相关的感染，如肺炎、脓胸、肾盂肾炎、膀胱炎、腹膜炎、脑膜炎和菌血症。由于报告不足，尤其是在印度，新生儿[病原体名称]感染的管理记录不充分。由于其多重耐药性以及文献中数据稀少，[病原体名称]的有效经验性治疗具有挑战性。我们报告了一例由[病原体名称]引起的菌血症罕见病例，该病例为一名患有中度呼吸窘迫综合征的早产新生儿，经成功治疗。我们还对新生儿年龄组的感染进行了综述。从今以后，在接受涉及使用侵入性设备和长期抗生素治疗的新生儿中，多重耐药的[病原体名称]应被视为一种HCAP。
