Immune Cells and Transcriptional Signatures Revealed Novel Regulators and Predict Clinical Response to Biologic Therapy in Ulcerative Colitis.
作者信息
Savkovic Suzana D
机构信息
Department of Pathology and Laboratory Medicine, Tulane University; 1430 Tulane Ave SL-79; New Orleans, LA 70112 USA.
出版信息
J Cell Immunol. 2021;3(5):343-347. doi: 10.33696/immunology.3.116.
Abstract
摘要
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2
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