LiqBioer：体液癌症生物标志物的人工 curated 数据库。
LiqBioer: a manually curated database of cancer biomarkers in body fluid.
机构信息
Department of Biochemistry and Molecular Biology, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin 150081, China.
Department of Systems Biology, College of Bioinformatics Science and Technology, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin 150081, China.
出版信息
Database (Oxford). 2022 Sep 2;2022. doi: 10.1093/database/baac077.
UNLABELLED
Cancer biomarkers are measurable indicators that play vital roles in clinical applications. Biomarkers in body fluids have gained considerable attention since the development of liquid biopsy, and their data volume is rapidly increasing. Nevertheless, current research lacks the compilation of published cancer body fluid biomarkers into a centralized and sustainable repository for researchers and clinicians, despite a handful of small-scale and specific data resources. To fulfill this purpose, we developed liquid biomarker (LiqBioer) containing 6231 manually curated records from 3447 studies, covering 3056 biomarkers and 74 types of cancer in 22 tissues. LiqBioer allows users to browse and download comprehensive information on body liquid biomarkers, including cancer types, source studies and clinical usage. As a comprehensive resource for body fluid biomarkers of cancer, LiqBioer is a powerful tool for researchers and clinicians to query and retrieve biomarkers in liquid biopsy.
DATABASE URL
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癌症生物标志物是可衡量的指标，在临床应用中起着至关重要的作用。随着液体活检的发展，体液中的生物标志物引起了相当大的关注，其数据量也在迅速增加。然而，尽管有少数小规模的特定数据资源，但目前的研究缺乏将已发表的癌症体液生物标志物编译成一个集中和可持续的研究人员和临床医生资源库。为了实现这一目标，我们开发了液体生物标志物（LiqBioer），其中包含 3447 项研究中的 6231 条手动整理的记录，涵盖了 22 种组织中的 3056 种生物标志物和 74 种癌症类型。LiqBioer 允许用户浏览和下载有关体液生物标志物的综合信息，包括癌症类型、来源研究和临床用途。作为癌症体液生物标志物的综合资源，LiqBioer 是研究人员和临床医生查询和检索液体活检中生物标志物的有力工具。
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