环状 RNA 癌症数据库：circRNAs 与癌症关联的人工整理数据库。
CircR2Cancer: a manually curated database of associations between circRNAs and cancers.
机构信息
School of Computer, Electronic and Information, Guangxi University, No.100 Daxue East Road, Nanning, Guangxi, 530004, China.
Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, No. 932 Lushan South Road, Changsha, Hunan, 410083, China .
出版信息
Database (Oxford). 2020 Jan 1;2020. doi: 10.1093/database/baaa085.
UNLABELLED
Accumulating evidences have shown that the deregulation of circRNA has close association with many human cancers. However, these experimental verified circRNA-cancer associations are not collected in any database. Here, we develop a manually curated database (circR2Cancer) that provides experimentally supported associations between circRNAs and cancers. The current version of the circR2Cancer contains 1439 associations between 1135 circRNAs and 82 cancers by extracting data from existing literatures and databases. In addition, circR2Cancer contains the information of cancer exacted from Disease Ontology and basic biological information of circRNAs from circBase. At the same time, circR2Cancer provides a simple and friendly interface for users to conveniently browse, search and download the data. It will be a useful and valuable resource for researchers to understanding the regulation mechanism of circRNA in cancers.
DATABASE URL
未标记
越来越多的证据表明，circRNA 的失调与许多人类癌症密切相关。然而，这些经过实验验证的 circRNA-癌症关联并未在任何数据库中收集。在这里，我们开发了一个手动编辑的数据库（circR2Cancer），该数据库提供了 circRNA 与癌症之间经过实验支持的关联。circR2Cancer 的当前版本通过从现有文献和数据库中提取数据，包含了 1135 个 circRNA 和 82 种癌症之间的 1439 种关联。此外，circR2Cancer 还包含了从疾病本体中提取的癌症信息和 circBase 中 circRNA 的基本生物学信息。同时，circR2Cancer 为用户提供了一个简单友好的界面，方便用户浏览、搜索和下载数据。它将成为研究人员了解 circRNA 在癌症中调控机制的有用且有价值的资源。
数据库网址
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