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澳大利亚维多利亚新兴毒品网络临床登记处:全州范围的非法药物监测和预警网络。

The Emerging Drugs Network of Australia - Victoria Clinical Registry: A state-wide illicit substance surveillance and alert network.

机构信息

Victorian Institute of Forensic Medicine, Melbourne, Victoria, Australia.

Department of Forensic Medicine, Monash University, Melbourne, Victoria, Australia.

出版信息

Emerg Med Australas. 2023 Feb;35(1):82-88. doi: 10.1111/1742-6723.14059. Epub 2022 Aug 29.

Abstract

OBJECTIVES

With an increasingly dynamic global illicit drug market, including the emergence of novel psychoactive substances, many jurisdictions have moved to establish toxicosurveillance systems to enable timely detection of harmful substances in the community. This paper describes the methodology for the Emerging Drugs Network of Australia - Victoria (EDNAV) project, a clinical registry focused on the collection of high-quality clinical and analytical data from ED presentations involving illicit drug intoxications. Drug intelligence collected from the project is utilised by local health authorities with the aim to identify patterns of drug use and emerging drugs of concern.

METHODS

The project involves 10 public hospital EDs in Victoria, Australia. Patients 16 years and over, presenting to a network ED with a suspected illicit drug-related toxicity and a requirement for venepuncture are eligible for inclusion in the study under a waiver of consent. Clinical and demographic parameters are documented by site-based clinicians and comprehensive toxicological analysis is conducted on patient blood samples via specialised forensic services. All data are then deidentified and compiled in a project specific database.

RESULTS

Cases are discussed in weekly multidisciplinary team meetings, with a view to identify potentially harmful substances circulating in the community. High-risk signals are escalated to key stakeholders to produce timely and proportionate public health alerts with a focus on harm minimisation.

CONCLUSIONS

The EDNAV project represents the first centralised system providing near real-time monitoring of community drug use in Victoria and is fundamental in facilitating evidence-based public health intervention.

摘要

目的

随着全球非法毒品市场日益活跃,包括新型精神活性物质的出现,许多司法管辖区已开始建立毒情监测系统,以实时检测社区中有害物质。本文介绍了澳大利亚维多利亚新兴毒品网络(EDNAV)项目的方法学,该项目是一个专注于收集涉及非法药物中毒的 ED 就诊中高质量临床和分析数据的临床登记处。从该项目收集的毒品情报由当地卫生当局利用,旨在识别药物使用模式和新出现的令人关切的毒品。

方法

该项目涉及澳大利亚维多利亚州的 10 家公立医院 ED。年龄在 16 岁及以上,因疑似与非法药物相关的毒性而到网络 ED 就诊且需要静脉穿刺的患者,在豁免同意的情况下有资格参与研究。临床和人口统计学参数由现场临床医生记录,并通过专门的法医服务对患者血液样本进行全面毒理学分析。然后,所有数据都被去识别并编译到一个特定于项目的数据库中。

结果

每周进行多学科团队会议讨论病例,以确定在社区中循环的潜在有害物质。将高风险信号上报给主要利益相关者,以便及时发布有针对性的公共卫生警报,重点是减少伤害。

结论

EDNAV 项目代表了第一个集中系统,提供了维多利亚州社区药物使用的近乎实时监测,对于促进基于证据的公共卫生干预至关重要。

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