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娱乐性药物毒性伴严重高热:现场快速治疗和临床过程。

Recreational drug toxicity with severe hyperthermia: Rapid onsite treatment and clinical course.

机构信息

Pulmonary and Critical Care Fellow, Division of Pulmonary and Critical Care Physiology and Medicine at Harbor-UCLA Medical Center, Torrance, CA, USA 90509..

Prehospital Care, Department of Emergency Medicine at Maimonides Medical Center, 4802 10th Ave, Brooklyn, NY, USA 11219.

出版信息

Am J Emerg Med. 2022 Dec;62:144.e5-144.e8. doi: 10.1016/j.ajem.2022.08.046. Epub 2022 Aug 28.

DOI:10.1016/j.ajem.2022.08.046
PMID:36055870
Abstract

Electronic dance music festivals have gained notoriety in the critical care and emergency medicine fields due to an alarming incidence of hospitalizations and deaths related to the high prevalence of recreational drug use. Recreational drug use toxicity, in part related to sympathomimetic toxidromes, may cause hyponatremia, seizures, rhabdomyolysis, hyperkalemia, acidosis, coagulopathy, circulatory shock, multi-organ failure, and even death. This wide-ranging syndrome has been referred to as psychostimulant drug-induced toxicity. Rapid onsite diagnosis and treatment, with attention to the A-B-C's of clinical emergencies, is essential to preserve life. We describe a patient presenting with the highest recorded core temperature in a survivor of psychostimulant drug-induced toxicity, and emphasize management principles of this life-threatening and increasingly prevalent condition.

摘要

电子舞曲音乐节在重症监护和急诊医学领域声名狼藉,因为与娱乐性药物使用高发相关的住院和死亡事件令人震惊。娱乐性药物使用毒性,部分与拟交感神经毒性综合征有关,可能导致低钠血症、癫痫发作、横纹肌溶解症、高钾血症、酸中毒、凝血功能障碍、循环性休克、多器官衰竭,甚至死亡。这种广泛的综合征被称为精神兴奋剂药物中毒。快速现场诊断和治疗,注意临床急症的 A-B-C,对于挽救生命至关重要。我们描述了一位患者,他是精神兴奋剂药物中毒存活者中记录到的核心体温最高的患者,并强调了这种危及生命且日益流行的疾病的治疗原则。

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