Borkenstein and Borkenstein Private Practice, Privatklinik Kreuzschwestern Graz, Kreuzgasse 35, 8010, Graz, Austria.
Accuratis, Practice for Refractive Eye Surgery, Hirschstrasse 1, 89073, Ulm, Germany.
BMC Ophthalmol. 2022 Sep 3;22(1):356. doi: 10.1186/s12886-022-02584-8.
The aim of this laboratory study is to objectively analyze the new hydrophobic, acrylic, enhanced monofocal intraocular lens Acunex Quantum (AN6Q) and compare it with the monofocal platform Acunex AN6. METHODS: Two IOL models were analyzed (Acunex Quantum AN6Q and Acunex AN6, Teleon Surgical, Spankeren, Netherlands), each having the same refractive power of + 22.0 D, on the optical bench with the OptiSpheric IOL PRO 2. The measurements followed the guidelines of the International Standard Organization with following parameters: ISO 2 cornea (+ 0,28 µ), ISO 11979/2, lens placement in situ in NaCl with 35° temperature, 546 nm and selection of different aperture sizes (3.0 mm vs 4.5 mm). The aberrations of each IOL were evaluated by the WaveMaster IOL 2, a high-resolution Shack-Hartmann sensor in reverse projection setup. An in-situ model eye was used according to ISO 11979 in NaCl (n = 1.337) with 546 nm, mask width 4.51. Zernike polynomials up to 10th order were determined by means of the measured wavefront that describe the optical properties of the IOL.
Through frequency modulation transfer function (mean) at 50 lp/mm (AN6Q/AN6 centered) was 0.687/0.731 (3.0 mm aperture) and 0.400/0.509 (4.5 mm aperture). The SR (mean) was 0.592/0.809 (3.0 mm) and 0.332/0.372 (4.5 mm). The MTF (mean) at 50 lp/mm (AN6Q/AN6 decentered by 1 mm) was 0.413/0.478 (3.0 mm) and 0.257/0.229 (4.5 mm). The SR (mean) was 0.393/0.404 (3.0 mm) and 0.183/0.212 (4.5 mm). The MTF (mean) at 50 lp/mm (AN6Q/AN6 tilted by 5°) was 0.508/0.710 (3.0 mm) and 0.337/0.513 (4.5 mm). The SR (mean) was 0.508/0.760 (3.0 mm) and 0.235/0.2372 (4.5 mm). AN6Q showed MTF peak of 0.55 with an enlarged depth of power of about 2.5 D and two cusps in the MTF curve. The spherical aberration Z 4-0 was about -0.21 µm and the secondary spherical aberration Z 6-0 was about 0.16 µm. No other relevant aberration showed up.
The new, enhanced monofocal AN6Q provides an extended range of focus with only slight decrease in contrast quality. Both types of the hydrophobic, acrylic Acunex IOL platform have its particular advantages in clinical settings and therefore its importance, respectively.
本实验室研究的目的是客观分析新型疏水性丙烯酸增强型单焦点人工晶状体 Acunex Quantum（AN6Q），并与单焦点平台 Acunex AN6 进行比较。
分析了两种 IOL 模型（Acunex Quantum AN6Q 和 Acunex AN6，Teleon Surgical，Spankeren，荷兰），每个模型的屈光力均为+22.0 D，在 OptiSpheric IOL PRO 2 光学台上进行测量。测量遵循国际标准化组织的指南，使用以下参数：ISO 2 角膜（+0.28µ），ISO 11979/2，在 35°C 温度下将透镜置于原位在 NaCl 中，546nm，选择不同孔径尺寸（3.0mm 与 4.5mm）。通过高分辨率反向投影设置中的 WaveMaster IOL 2 对每个 IOL 的像差进行评估。根据 ISO 11979 在 NaCl 中使用原位模型眼（n=1.337），546nm，掩模宽度为 4.51。通过测量波前确定高达第 10 阶的泽尼克多项式，这些多项式描述了 IOL 的光学特性。
在 50 lp/mm 时，调制传递函数（均值）（AN6Q/AN6 中心）为 0.687/0.731（3.0mm 孔径）和 0.400/0.509（4.5mm 孔径）。SR（均值）为 0.592/0.809（3.0mm）和 0.332/0.372（4.5mm）。在 50 lp/mm 时，调制传递函数（均值）（AN6Q/AN6 偏离 1mm）为 0.413/0.478（3.0mm）和 0.257/0.229（4.5mm）。SR（均值）为 0.393/0.404（3.0mm）和 0.183/0.212（4.5mm）。在 50 lp/mm 时，调制传递函数（均值）（AN6Q/AN6 倾斜 5°）为 0.508/0.710（3.0mm）和 0.337/0.513（4.5mm）。SR（均值）为 0.508/0.760（3.0mm）和 0.235/0.2372（4.5mm）。AN6Q 显示出 0.55 的 MTF 峰值，其功率扩展范围约为 2.5 D，并且在 MTF 曲线中有两个尖峰。球差 Z4-0 约为-0.21µm，二次球差 Z6-0 约为 0.16µm。没有出现其他相关像差。
新型增强型单焦点 AN6Q 提供了扩展的焦点范围，仅略微降低对比度质量。疏水性丙烯酸 Acunex IOL 平台的两种类型在临床环境中都有其特定的优势，因此都具有重要性。
