Ceska Slov Farm. 2022 Summer;71(3):98-102.
The research was performed on 80 male rats of the Wistar line. Animals of two age groups were used: adults (10-12 months) and old (22-25 months). The obtained data show that the development of immobilization stress in adult and aged rats are accompanied by the formation of a characteristic complex of changes in the phospholipid composition of the myocardium. Intraperitoneal injection of the chokeberry extract (Aronia melanocarpa) at a dose of 0.2 g/kg 60 minutes before the immobilization has limited stress modulation of myocardial phospholipid composition in aged animals. Thus, the extract of Aronia melanocarpa increases the myocardial resistance to the injury effect of stress.
这项研究是在 80 只雄性 Wistar 系大鼠上进行的。使用了两个年龄组的动物：成年（10-12 个月）和老年（22-25 个月）。获得的数据表明，成年和老年大鼠的固定应激发展伴随着心肌磷脂组成的特征性变化的形成。在固定前 60 分钟，以 0.2 g/kg 的剂量腹腔注射黑果腺肋花楸提取物（Aronia melanocarpa），可限制老年动物心肌磷脂组成的应激调节作用。因此，黑果腺肋花楸提取物增加了心肌对应激损伤效应的抵抗力。
