Govrin-Yehudain J, Moscona A R, Calderon N, Hirshowitz B
Ann Plast Surg. 1987 Jun;18(6):465-9. doi: 10.1097/00000637-198706000-00001.
Twenty-one patients with hemangiomas on the face and lip who were treated with injections of sclerosing agents are discussed. The mode of action of these drugs was also studied experimentally on rats, which were injected through the pampiniform plexus of the spermatic cord. In the clinical study all patients showed satisfactory resolution of the hemangiomas with commensurate improvement in their appearance. The experimental study provides an explanation for the replacement of blood vessels by young connective tissue.
本文讨论了21例接受硬化剂注射治疗面部和唇部血管瘤的患者。还通过对大鼠精索蔓状静脉丛注射这些药物进行了实验性研究,以探究其作用方式。在临床研究中,所有患者的血管瘤均得到了令人满意的消退,外观也有相应改善。实验研究为年轻结缔组织取代血管提供了解释。