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短角膜水平直径患者行可植入式胶原晶状体植入术的安全性及前房结构

Safety and anterior chamber structure of evolution implantable Collamer lens implantation with short white-to-white corneal diameters.

作者信息

Chen Xun, Chen Fang, Wang Xuanqi, Xu Yilin, Cheng Mingrui, Han Tian, Wang Xiaoying, Zhou Xingtao

机构信息

Fudan University Eye Ear Nose and Throat Hospital, Shanghai, China.

National Health Commission Key Lab of Myopia, Fudan University, Shanghai, China.

出版信息

Front Med (Lausanne). 2022 Aug 17;9:928245. doi: 10.3389/fmed.2022.928245. eCollection 2022.

Abstract

INTRODUCTION

To evaluate the safety and anterior chamber structure of implantation of the Evolution (EVO) implantable Collamer lens (EVO-ICL) in patients with short white-to-white (WTW) corneal diameters.

MATERIALS AND METHODS

The study population was divided into two groups: the experimental group (34 eyes of 34 patients) with WTW corneal diameters of ≤10.6 mm and the control group (59 eyes of 59 patients) with WTW corneal diameters of >10.6 mm. The outcome measures included uncorrected distance visual acuity, corrected distance visual acuity, refractive power, intraocular pressure (IOP), anterior chamber angle, depth, volume, and vault.

RESULTS

The safety indices of the experimental and control groups were 1.17 ± 0.30 and 1.12 ± 0.14, respectively ( > 0.05); the effectiveness indices were 1.16 ± 0.31 and 1.07 ± 0.17, respectively ( > 0.05). The simulation curves of the expected and actual corrections in the experimental and control groups were y = 0.9876x - 0.0927 and y = 0.9799x + 0.0343, respectively. There were no significant differences between the IOPs and anterior chamber structures of the two groups ( > 0.05). The average vaults of the experimental and control groups were 395.76 ± 155.32 and 389.49 ± 135.01 μm, respectively ( > 0.05).

CONCLUSION

EVO-ICL implantation in patients with short WTW corneal diameters (≤ 10.6 mm) was determined to be a safe, effective, and predictable method for correcting myopia. The changes in the anterior chamber structure were still within normal limits after the surgery, the IOP remained stable, and the ideal vault was achieved after the surgery.

摘要

引言

评估在白到白(WTW)角膜直径较短的患者中植入Evolution(EVO)可植入式胶原晶状体(EVO-ICL)的安全性和前房结构。

材料与方法

研究人群分为两组:实验组(34例患者的34只眼),WTW角膜直径≤10.6mm;对照组(59例患者的59只眼),WTW角膜直径>10.6mm。观察指标包括未矫正远视力、矫正远视力、屈光力、眼压(IOP)、前房角、深度、容积和拱高。

结果

实验组和对照组的安全指数分别为1.17±0.30和1.12±0.14(>0.05);有效性指数分别为1.16±0.31和1.07±0.17(>0.05)。实验组和对照组预期矫正与实际矫正的模拟曲线分别为y = 0.9876x - 0.0927和y = 0.9799x +  0.0343。两组的眼压和前房结构无显著差异(>0.05)。实验组和对照组的平均拱高分别为395.76±155.32和389.49±135.01μm(>0.05)。

结论

对于WTW角膜直径较短(≤10.6mm)的患者,植入EVO-ICL被确定为一种安全、有效且可预测的近视矫正方法。术后前房结构变化仍在正常范围内,眼压保持稳定,术后实现了理想的拱高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d013/9428310/35d9c1ea5fed/fmed-09-928245-g001.jpg

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