Department of Ophthalmology, Shanghai Eye and ENT Hospital, Fudan University, Shanghai, China.
NHC Key Laboratory of Myopia, Fudan University; Key Laboratory of Myopia, Chinese Academy of Medical Science; and Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China.
Invest Ophthalmol Vis Sci. 2021 Jan 4;62(1):7. doi: 10.1167/iovs.62.1.7.
To investigate the distribution of white-to-white (WTW) distance and its associations with other biometric parameters in Chinese cataractous eyes.
Data on 39,986 eyes from 23,627 Chinese cataract patients were analyzed. Ocular biometric parameters, including WTW distance, corneal curvature, anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), and axial length (AL), were obtained using the ZEISS IOLMaster 700.
The mean age of patients was 63.7 ± 12.4 years, and 57.61% were female. The mean WTW distance was 11.69 ± 0.46 mm. The WTW distance was larger in male patients than in female patients for all age groups (all P < 0.001). The WTW distance was positively correlated with corneal curvature and ACD and negatively correlated with age, LT, and CCT (all P < 0.001). Multivariable analysis revealed that a larger WTW distance was associated with younger age; male gender; larger corneal curvature, ACD, and LT; and thinner CCT (all P < 0.001). Notably, the association between WTW distance and AL was not linear. As the AL increased, the WTW distance initially increased, reached a peak in the group with ALs of 24.5 to 26 mm, and then slowly decreased. However, all of the myopic eyes (AL > 24.5 mm) still had larger WTWs than the normal and short eyes (AL ≤ 24.5 mm).
In Chinese cataractous eyes, the WTW distance was larger in younger male patients with flatter corneas, deeper anterior chambers, thicker lenses, and thinner central corneas. The association between WTW distance and AL was not linear, and WTW distance was the largest in eyes with ALs of 24.5 to 26 mm.
探讨中国人白内障眼中的眼白-眼白（WTW）距离分布及其与其他生物测量参数的关系。
分析了 23627 名中国人白内障患者的 39986 只眼的数据。使用 ZEISS IOLMaster 700 获得眼生物测量参数，包括 WTW 距离、角膜曲率、前房深度（ACD）、晶状体厚度（LT）、中央角膜厚度（CCT）和眼轴长度（AL）。
患者的平均年龄为 63.7±12.4 岁，57.61%为女性。平均 WTW 距离为 11.69±0.46mm。所有年龄组中，男性患者的 WTW 距离均大于女性患者（均 P<0.001）。WTW 距离与角膜曲率和 ACD 呈正相关，与年龄、LT 和 CCT 呈负相关（均 P<0.001）。多变量分析显示，较大的 WTW 距离与较年轻的年龄、男性性别、较大的角膜曲率、ACD 和 LT 以及较薄的 CCT 相关（均 P<0.001）。值得注意的是，WTW 距离与 AL 之间的关系不是线性的。随着 AL 的增加，WTW 距离最初增加，在 AL 为 24.5 至 26mm 的组中达到峰值，然后缓慢下降。然而，所有近视眼（AL>24.5mm）的 WTW 仍大于正常眼和短眼（AL≤24.5mm）。
在中国人白内障眼中，WTW 距离在较年轻的男性患者中较大，这些患者的角膜较平坦，前房较深，晶状体较厚，中央角膜较薄。WTW 距离与 AL 之间的关系不是线性的，WTW 距离在 AL 为 24.5 至 26mm 的眼中最大。
