Suppr超能文献

尿道下裂:一项全面综述,涵盖其胚胎学、病因学及手术技术

Hypospadias: A Comprehensive Review Including Its Embryology, Etiology and Surgical Techniques.

作者信息

Halaseh Sattam A, Halaseh Shahed, Ashour Mohannad

机构信息

General and Colorectal Surgery, Torbay Hospital, Torbay and South Devon NHS Foundation Trust, Torquay, GBR.

Surgery, Jordan University Hospital, Amman, JOR.

出版信息

Cureus. 2022 Jul 31;14(7):e27544. doi: 10.7759/cureus.27544. eCollection 2022 Jul.

Abstract

Hypospadias is among the most prevalent urogenital malformations in male newborns. It is characterized by the displacement of the urethral meatus to the ventral side of the penis, an aberrant ventral curve of the penis referred to as "chordee," and an abnormally arranged foreskin with a "hood" found dorsally and lacking foreskin ventrally. Patients may have an extra genitourinary abnormality based on the area of the lesion. In around 70% of cases, the urethral meatus is positioned distally to the shaft, representing a milder form of the disease. The remaining 30% of cases are located proximally, are more complicated, and require further evaluation. Although the origin of hypospadias is mostly obscure, several suggestions exist about genetic susceptibility and hormonal factors. The objective of hypospadias restoration is to restore aesthetic and functional regularity, and surgery is currently advised at a young age, mostly between six and 18 months. At any age, hypospadias can be repaired with an equivalent risk of complications, functional outcomes, and aesthetic outcomes. However, the best age of treatment is still undetermined. Even though the long-term effects on appearance and sexual function are usually good, males may be less likely to make the first move after rectification. Also, people who have hypospadias treated are twice as likely to have problems with their lower urinary tract. These problems can last for years after the initial repair.

摘要

尿道下裂是男性新生儿中最常见的泌尿生殖系统畸形之一。其特征为尿道口移位至阴茎腹侧、阴茎异常的腹侧弯曲即“阴茎下弯”,以及包皮异常排列,背侧有“头巾样”结构,腹侧缺乏包皮。根据病变区域,患者可能存在额外的泌尿生殖系统异常。约70%的病例中,尿道口位于阴茎体远端,代表病情较轻的一种形式。其余30%的病例尿道口位于近端,病情更复杂,需要进一步评估。尽管尿道下裂的病因大多不明,但关于遗传易感性和激素因素有几种推测。尿道下裂修复的目的是恢复美观和功能正常,目前建议在幼年时进行手术,大多在6至18个月之间。在任何年龄,尿道下裂都可以修复,并发症风险、功能结局和美观效果相当。然而,最佳治疗年龄仍未确定。尽管对外观和性功能的长期影响通常良好,但矫正后男性可能不太可能主动发起性行为。此外,接受尿道下裂治疗的人下尿路出现问题的可能性是正常人的两倍。这些问题在初次修复后可能会持续数年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7af/9428502/159fd69b2ed5/cureus-0014-00000027544-i01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验