Meta 分析护理干预对 2 型糖尿病患儿的影响。
Meta-Analysis of the Effect of Nursing Intervention on Children with Type 2 Diabetes.
机构信息
Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, Zhejiang 313000, China.
出版信息
Comput Math Methods Med. 2022 Aug 25;2022:6185739. doi: 10.1155/2022/6185739. eCollection 2022.
OBJECTIVE
To systematically evaluate the effect of nursing intervention on children with type 2 diabetes.
METHODS
The randomized controlled trials (RCTs) on nursing intervention in children with type 2 diabetes in CNKI, VIP, WanFang, Chinese Biomedical Database (CBM), PubMed, The Cochrane Library, Embase, and Science were searched by the computer until July 2022. Two evaluators reviewed the articles, selected the information, and assessed their quality according to the inclusion criteria and exclusion criteria and then carried out meta-analysis with RevMan 5.3.
RESULTS
A total of 5 RCT studies were kept, including 319 patients with type 2 diabetes (≤21 years old), where 162 patients were in the nursing group and 157 patients were in the control group. Meta-analysis revealed that, compared with routine nursing, nursing intervention could effectively control children's fasting blood glucose (FBG) (MD = -1.68, 95% CI (-2.19, -1.17), < 0.00001), 2 h postprandial blood glucose (2hPG) (MD = -4.01, 95% CI (-4.70, -3.33), < 0.00001), fasting insulin (FINS) (MD = -7.42, 95% CI (-10.63, -4.20), < 0.00001), 2 h postprandial insulin (2hINS) (MD = -58.18, 95% CI (-103.24, -13.11), = 0.01), triglycerides (TG) (MD = -0.41, 95% CI (-0.56, -0.25), < 0.00001), and systolic blood pressure (SBP) (MD = -8.85, 95% CI (-14.67, -3.03), = 0.003) and effectively maintain patients' blood glucose at a normal level (MD = -8.85, 95% CI (-14.67, -3.03), = 0.003), where all the differences were statistically significant.
CONCLUSION
The existing evidence showed that nursing intervention has a significant effect in controlling normal blood glucose and improving insulin utilization in children with type 2 diabetes, which can effectively improve the therapeutic effect on children.
目的
系统评价护理干预对 2 型糖尿病患儿的影响。
方法
计算机检索中国知网、维普、万方、中国生物医学文献数据库、PubMed、The Cochrane Library、Embase 和 Science 中关于护理干预 2 型糖尿病患儿的随机对照试验（RCT），检索时限均为建库至 2022 年 7 月。由 2 位评价员按照纳入和排除标准筛选文献、提取资料并评价纳入研究的质量后，采用 RevMan 5.3 软件进行 Meta 分析。
结果
共纳入 5 项 RCT 研究，包括 319 例 2 型糖尿病患儿（年龄≤21 岁），其中护理组 162 例，对照组 157 例。Meta 分析结果显示，与常规护理相比，护理干预能更有效地控制患儿空腹血糖（FBG）〔MD=-1.68，95%CI（-2.19，-1.17），<0.00001〕、餐后 2 h 血糖（2hPG）〔MD=-4.01，95%CI（-4.70，-3.33），<0.00001〕、空腹胰岛素（FINS）〔MD=-7.42，95%CI（-10.63，-4.20），<0.00001〕、餐后 2 h 胰岛素（2hINS）〔MD=-58.18，95%CI（-103.24，-13.11），=0.01〕、三酰甘油（TG）〔MD=-0.41，95%CI（-0.56，-0.25），<0.00001〕和收缩压（SBP）〔MD=-8.85，95%CI（-14.67，-3.03），=0.003〕，使患儿血糖更平稳地维持在正常水平〔MD=-8.85，95%CI（-14.67，-3.03），=0.003〕，差异均有统计学意义。
结论
现有证据表明，护理干预在控制 2 型糖尿病患儿血糖正常及改善胰岛素利用方面具有显著效果，能有效提高患儿的治疗效果。
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