Laldinsangi C
Department of Life Sciences, Pachhunga University College, Mizoram University (A Central University), Aizawl, 796001, Mizoram, India.
Heliyon. 2022 Aug 24;8(8):e10386. doi: 10.1016/j.heliyon.2022.e10386. eCollection 2022 Aug.
The search and development of new drugs for the treatment of numerous illnesses afflicting humans of all ages is an unending endeavour. Moreover, there is constant demand to identify more compounds exhibiting pharmacological properties with improved efficacy and minimal side effects compared to the existing ones. Plants have always served as rich sources of pharmaceuticals, and offer better advantages than synthetic compounds in terms of diversity, production scale and safety. is a traditional medicinal plant that is widely distributed in East Asia. Apart from its consumption as a delicacy in many countries, it has a rich history of medicinal use and numerous studies have reported its pharmacological activity against inflammation, cancer, viruses, bacteria, hyperglycaemia, obesity, etc. The various phytoconstituents that have been isolated from this plant include flavonoids, phenolic acids, volatile/essential oils and alkaloids whose therapeutic potentials are yet to be fully harnessed. This review provides an updated summary of the biological activity and therapeutic potential of , its phytocompounds and derivatives. The amalgamation of traditional plant-derived medicines with modern scientific methods can provide better insights to their mechanism of action and also contribute greatly to the discovery and synthesis of new pharmaceuticals.
寻找和开发用于治疗困扰各年龄段人类的众多疾病的新药是一项永无止境的努力。此外,人们一直需要鉴定出更多与现有化合物相比具有更高疗效和最小副作用的药理特性的化合物。植物一直是药物的丰富来源,并且在多样性、生产规模和安全性方面比合成化合物具有更好的优势。[植物名称]是一种广泛分布于东亚的传统药用植物。除了在许多国家作为美味食用外,它还有丰富的药用历史,许多研究报告了其对炎症、癌症、病毒、细菌、高血糖、肥胖等的药理活性。从这种植物中分离出的各种植物成分包括黄酮类化合物、酚酸、挥发性/精油和生物碱,其治疗潜力尚未得到充分利用。本综述提供了[植物名称]、其植物化合物和衍生物的生物活性和治疗潜力的最新总结。传统植物源药物与现代科学方法的结合可以更好地洞察其作用机制,也将极大地有助于新药物的发现和合成。