Lau W Y, Chong K K, Fan S T, Chu K W, Yip W C, Poon G P, Wong K K
Ann Surg. 1987 Aug;206(2):142-7. doi: 10.1097/00000658-198708000-00005.
A prospective study to determine the safety and effectiveness of choledochoscopy in acute cholangitis and acute suppurative cholangitis due to common bile duct stones was conducted on 70 patients. Common bile duct pressures determined on the first 20 patients showed that choledochoscopy was unlikely to cause cholangiovenous reflux. Laboratory and clinical parameters revealed that choledochoscopy did not cause septicemia, worsen cholangitis, or provoke acute pancreatitis. There was no iatrogenic injury during choledochoscopy, and the choledochoscopic views were minimally affected by cholangitis. Choledochoscopy detected overlooked stones after conventional methods of exploration of common bile ducts in 14.3% of patients and it helped to remove impacted stones in 2.9% of patients. As a result, the incidence of retained stones after choledochoscopy was 1.4%. Time spent in choledochoscopy was short, and the total postoperative septic complication rate was only 10%. There was no operative mortality. It is concluded that choledochoscopy is safe and effective in cholangitis.
对70例因胆总管结石导致急性胆管炎和急性化脓性胆管炎的患者进行了一项前瞻性研究,以确定胆管镜检查在其中的安全性和有效性。对前20例患者测定的胆总管压力显示,胆管镜检查不太可能引起胆管静脉反流。实验室和临床参数表明,胆管镜检查不会导致败血症、加重胆管炎或引发急性胰腺炎。胆管镜检查期间未发生医源性损伤,胆管炎对胆管镜视野的影响最小。胆管镜检查在14.3%的患者中发现了常规胆总管探查方法遗漏的结石,并帮助2.9%的患者取出了嵌顿结石。结果,胆管镜检查后残留结石的发生率为1.4%。胆管镜检查耗时短,术后败血症并发症的总发生率仅为10%。无手术死亡病例。结论是胆管镜检查在胆管炎中是安全有效的。