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含糖饮料的摄入与老年人认知功能的下降有关:来自全国健康和营养调查及食物模式等效数据库。

Sugar-sweetened beverages consumption is associated with worse cognitive functions in older adults: from the national health and nutrition examination survey and food patterns equivalents database.

机构信息

Department of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao, People's Republic of China.

出版信息

Nutr Neurosci. 2023 Oct;26(10):1011-1018. doi: 10.1080/1028415X.2022.2115242. Epub 2022 Sep 5.

DOI:10.1080/1028415X.2022.2115242
PMID:36062834
Abstract

This study aimed to investigate the association between sugar-sweetened beverages (SSB) consumption (including individual SSB) and cognitive function from the National Health and Nutrition Examination Survey (NHANES) and Food Patterns Equivalents Database (FPED) and whether it is age-dependent. Older adults aged 60 years old and over were included during the NHANES 2011-2014. SSB consumption was defined as the amount of added sugar obtained by connecting the NHANES and FPED. Cognitive function tests included the consortium to establish a registry for Alzheimer's disease test, Animal Fluency Test and Digit Symbol Substitution Test. We calculated z-score using the average of the total standardized scores on three cognitive tests to estimate the level of whole cognition. Multi-variable linear regression models and interaction analysis were conducted in this study. For individual SSB types, increased carbonated soft drinks, sweetened tea, fruit drinks, energy drinks, and sport drinks were all significantly linked to declined cognitive function ( < 0.05), respectively. Nevertheless, interaction effects by age groups were not significant ( for interaction > 0.05). SSB consumption (including individual SSB) was negatively associated with cognitive function, which was not age-dependent. Future studies may advance the knowledge in the field considering the association between SSB consumption and cognitive function.

摘要

本研究旨在通过国家健康和营养检查调查(NHANES)和食物模式等效数据库(FPED)调查含糖饮料(SSB)摄入(包括个体 SSB)与认知功能之间的关联,以及这种关联是否存在年龄依赖性。NHANES 2011-2014 期间纳入年龄在 60 岁及以上的老年人。SSB 的摄入量定义为通过连接 NHANES 和 FPED 获得的添加糖量。认知功能测试包括建立阿尔茨海默病注册协会的测试、动物流畅性测试和数字符号替代测试。我们使用三种认知测试的总标准化分数的平均值计算 z 分数,以估计整体认知水平。本研究进行了多变量线性回归模型和交互分析。对于个体 SSB 类型,碳酸软饮料、加糖茶、果汁饮料、能量饮料和运动饮料的摄入量增加均与认知功能下降显著相关(<0.05)。然而,年龄组之间的交互作用不显著(交互作用>0.05)。SSB 的摄入(包括个体 SSB)与认知功能呈负相关,与年龄无关。未来的研究可能会考虑 SSB 摄入与认知功能之间的关联,从而推进该领域的知识。

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