Department of Cardiology, Birmingham Women's & Children's NHS Foundation Trust, Birmingham, UK.
Anaesthesia & Intensive Care department, Sudan Medical Specialization Board, Khartoum, Sudan.
Future Cardiol. 2022 Nov;18(11):901-913. doi: 10.2217/fca-2022-0053. Epub 2022 Sep 5.
To evaluate outcomes of interventions for severe aortic valve stenosis (AS), whether it is done by surgical aortic valvotomy (SAV) or balloon aortic dilatation (BAD). Eleven studies with total number of 1733 patients; 743 patients had SAV, while 990 patients received BAD. There was no significant difference in early mortality (odds ratio [OR]: 0.96, p = 0.86), late mortality (OR: 1.28, p = 0.25), total mortality (OR: 1.10, p = 0.56), and freedom from aortic valve replacement (OR: 1.00, p = 1.00). Reduction of aortic systolic gradient was significantly higher in the SAV group (OR: 2.24, p = 0.00001), and postprocedural AR rate was lower in SAV group (OR: 0.21, p = 0.00001). SAV is associated with better reduction of aortic systolic gradient and lesser post procedural AR which reduce when compared with BAD.
为了评估严重主动脉瓣狭窄（AS）干预措施的结果，无论是通过外科主动脉瓣切开术（SAV）还是球囊主动脉扩张术（BAD）进行。共有 11 项研究，总计 1733 例患者；743 例患者接受了 SAV，990 例患者接受了 BAD。早期死亡率（比值比 [OR]：0.96，p=0.86）、晚期死亡率（OR：1.28，p=0.25）、总死亡率（OR：1.10，p=0.56）和免于主动脉瓣置换（OR：1.00，p=1.00）均无显著差异。SAV 组主动脉收缩期梯度降低更显著（OR：2.24，p=0.00001），SAV 组术后 AR 发生率较低（OR：0.21，p=0.00001）。与 BAD 相比，SAV 与主动脉收缩期梯度降低和术后 AR 发生率降低有关。
