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T cells regulate antibody affinity and determine the outcomes of anaphylaxis.

作者信息

Lama Jyoti K, Kita Hirohito

机构信息

Department of Immunology, Mayo Clinic Rochester and Mayo Clinic Arizona, Scottsdale, Ariz; Immunology Program, Mayo Graduate School of Biomedical Sciences, Rochester and Scottsdale, Ariz.

Department of Immunology, Mayo Clinic Rochester and Mayo Clinic Arizona, Scottsdale, Ariz; Division of Allergy, Asthma and Clinical Immunology and Department of Medicine, Mayo Clinic Arizona, Scottsdale, Ariz.

出版信息

J Allergy Clin Immunol. 2022 Nov;150(5):1042-1044. doi: 10.1016/j.jaci.2022.08.018. Epub 2022 Sep 3.

DOI:10.1016/j.jaci.2022.08.018
PMID:36063853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10452041/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0431/10452041/c4985669aac6/nihms-1924894-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0431/10452041/c4985669aac6/nihms-1924894-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0431/10452041/c4985669aac6/nihms-1924894-f0001.jpg

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J Allergy Clin Immunol. 2022 Jul;150(1):178-191.e9. doi: 10.1016/j.jaci.2022.01.014. Epub 2022 Jan 29.
2
Sialylation of immunoglobulin E is a determinant of allergic pathogenicity.免疫球蛋白 E 的唾液酸化是过敏发病机制的决定因素。
Nature. 2020 Jun;582(7811):265-270. doi: 10.1038/s41586-020-2311-z. Epub 2020 May 20.
3
IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants.免疫接种不同佐剂后，生发中心反应期间 IgG Fc 岩藻糖化受到调节。
J Allergy Clin Immunol. 2020 Sep;146(3):652-666.e11. doi: 10.1016/j.jaci.2020.04.059. Epub 2020 May 21.
4
Identification of a T follicular helper cell subset that drives anaphylactic IgE.鉴定出驱动过敏 IgE 的滤泡辅助 T 细胞亚群。
Science. 2019 Aug 30;365(6456). doi: 10.1126/science.aaw6433. Epub 2019 Aug 1.
5
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6
T Follicular Helper Cell Biology: A Decade of Discovery and Diseases.滤泡辅助性 T 细胞生物学：十年的发现与疾病
Immunity. 2019 May 21;50(5):1132-1148. doi: 10.1016/j.immuni.2019.04.011.
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