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衰弱前期老年人在新冠大流行期间身体功能、认知、抑郁情绪和生活质量的演变:一项纵向队列研究(Covid-Mefap)。

Evolution of physical function, cognition, depressive mood, and quality of life during the Covid-19 pandemic in prefrail elderly people: A longitudinal cohort study (Covid-Mefap).

机构信息

Dr. Castroviejo Primary Care Health Center, Northern health directorate, Madrid Health Service (SERMAS), Madrid, Spain; Department of Medicine, Unit of Family Medicine and Primary Care, Faculty of Medicine, Universidad Autónoma de Madrid, Spain; Hospital La Paz Institute for Health Research IdiPAZ, Madrid, Spain.

Primary Care Research Unit, Primary Care Health Management, Madrid Health Service (SERMAS), Madrid, Spain; Research Network on Health Services in Chronic Diseases (REDISSEC) and Research Network On Chronicity, Primary Health Care and Health Promotion (RICORS-RICAPPS), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

出版信息

Exp Gerontol. 2022 Oct 15;168:111946. doi: 10.1016/j.exger.2022.111946. Epub 2022 Sep 5.

Abstract

UNLABELLED

Confinement due to the COVID-19 pandemic has had a major impact on the living habits and health of the population, notably in the pre-frail elderly. This study aimed to study the effect of the COVID-19 pandemic on the physical function, mental function (cognition and mood), and quality of life of pre-frail elderly individuals over 70 years of age following confinement as well as to analyze the variables associated with the observed changes.

METHODS

Observational study of a cohort of pre-frail community-dwelling older adults over 70 years of age during the COVID-19 pandemic conducted in primary care.

VARIABLES

The main outcome variables were recorded during face-to-face interviews between December 14 of 2020 and August 12 of 2021 using scales for the evaluation of physical function (Short Physical Performance Battery), cognition (Lobo's Mini-Examen Cognoscitivo), depressive mood (Geriatric Depression Scale), and quality of life (EuroQol-5D-3L). Covariates: sociodemographic data and variables related to the pandemic and general health (social support network, COVID-19 infection, exercising, and leisure activities) were also collected.

ANALYSIS

The Student's t-test for paired samples and multivariate linear regression models were employed for the statistical analyses.

RESULTS

Ninety-two subjects were included in the study. Physical function, cognition, and depressive mood improved during the pandemic, whereas no changes were observed in quality of life. Suffering from COVID-19 was associated with deterioration of the cognitive function (-1.460; CI95%: -2.710 to -0.211).

CONCLUSION

Confinement due to the COVID-19 pandemic was not associated with a decline in physical function, cognition, depressive mood, or quality of life in pre-frail individuals over 70 years of age.

摘要

目的

研究 COVID-19 大流行对 70 岁以上衰弱前期老年人的身体机能、心理功能(认知和情绪)和生活质量的影响,并分析观察到的变化相关的变量。

方法

在 COVID-19 大流行期间,在初级保健中对 70 岁以上的衰弱前期社区居住老年人进行了一项队列观察性研究。

主要结果变量是在 2020 年 12 月 14 日至 2021 年 8 月 12 日期间通过身体机能评估量表(短体能表现电池)、认知(洛博迷你认知检查)、抑郁情绪(老年抑郁量表)和生活质量(EuroQol-5D-3L)进行面对面访谈时记录的。

协变量

还收集了社会人口统计学数据以及与大流行和一般健康相关的变量(社会支持网络、COVID-19 感染、锻炼和休闲活动)。

分析

采用配对样本学生 t 检验和多变量线性回归模型进行统计分析。

结果

本研究共纳入 92 例患者。身体机能、认知和抑郁情绪在大流行期间有所改善,而生活质量无变化。患有 COVID-19 与认知功能下降有关(-1.460;95%CI:-2.710 至-0.211)。

结论

COVID-19 大流行期间的隔离对 70 岁以上衰弱前期个体的身体机能、认知、抑郁情绪或生活质量没有下降的影响。

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