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文拉法辛致青少年女性泌乳:病例报告。

Venlafaxine-related galactorrhea in an adolescent female: A case report.

机构信息

University of Pittsburgh School of Nursing, 3500 Victoria St., Pittsburgh, PA 15213, United States of America.

University of Pittsburgh School of Nursing, 3500 Victoria St., Pittsburgh, PA 15213, United States of America.

出版信息

Arch Psychiatr Nurs. 2022 Oct;40:106-108. doi: 10.1016/j.apnu.2022.06.001. Epub 2022 Jun 6.

Abstract

Hyperprolactinemia with galactorrhea is a well-documented adverse effect of some psychotropic medications. While advanced practice psychiatric nurses are likely familiar with hyperprolactinemia with galactorrhea as an adverse effect of antipsychotics, they may be less familiar with hyperprolactinemia with galactorrhea associated with antidepressants, an adverse effect that is far less common. Advanced practice psychiatric nurses must be able to identify hyperprolactinemia and galactorrhea in patients and must be able to evaluate and manage antidepressant-related hyperprolactinemia with galactorrhea. Thus, this case report describes hyperprolactinemia with galactorrhea in a teenage female prescribed venlafaxine for the treatment of major depressive disorder and posttraumatic stress disorder. To our knowledge, this is the first case report that describes galactorrhea related to a reuptake inhibitor (SNRI) in an adolescent.

摘要

高泌乳素血症伴溢乳是一些精神药物的一种明确记载的不良反应。虽然高级实践精神科护士可能熟悉抗精神病药引起的高泌乳素血症伴溢乳这一不良反应,但他们可能不太熟悉与抗抑郁药相关的高泌乳素血症伴溢乳这一不良反应,后者更为少见。高级实践精神科护士必须能够识别患者的高泌乳素血症和溢乳,并能够评估和管理与抗抑郁药相关的高泌乳素血症伴溢乳。因此,本病例报告描述了一名青少年女性因治疗重度抑郁症和创伤后应激障碍而服用文拉法辛引起的高泌乳素血症伴溢乳。据我们所知,这是首例描述青少年使用再摄取抑制剂(SNRI)相关溢乳的病例报告。

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