de Albuquerque Beatriz Helena Dantas Rodrigues, de Oliveira Maryana Thalyta Ferreira Camara, Aderaldo Janaína Ferreira, de Medeiros Garcia Torres Mychelle, Lanza Daniel Carlos Ferreira
Laboratório de Biologia Molecular Aplicada - LAPLIC, Departamento de Bioquímica, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal, RN, CEP: 59072-970, Brazil.
Rede Nordeste de Biotecnologia - RENORBIO, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.
Basic Clin Androl. 2022 Sep 6;32(1):16. doi: 10.1186/s12610-022-00165-9.
The seminal virome and its implications for fertility remain poorly understood. To date, there are no defined panels for the detection of viruses of clinical interest in seminal samples.
In this study, we characterized the human seminal virome based on more than 1,000 studies published over the last five years.
The number of studies investigating viruses that occur in human semen has increased, and to date, these studies have been mostly prospective or related to specific clinical findings. Through the joint analysis of all these studies, we have listed the viruses related to the worsening of seminal parameters and propose a new panel with the main viruses already described that possibly affect male fertility and health. This panel can assist in evaluating semen quality and serve as a tool for investigation in cases of infertility.
精液病毒组及其对生育能力的影响仍知之甚少。迄今为止，尚无用于检测精液样本中具有临床意义病毒的既定检测组合。
在本研究中，我们基于过去五年发表的1000多项研究对人类精液病毒组进行了特征分析。
研究人类精液中出现的病毒的研究数量有所增加，迄今为止，这些研究大多是前瞻性的或与特定临床发现相关。通过对所有这些研究的联合分析，我们列出了与精液参数恶化相关的病毒，并提出了一个新的检测组合，其中包含已描述的可能影响男性生育能力和健康的主要病毒。该检测组合可协助评估精液质量，并作为不育症病例调查的工具。
