Department of Urology, Mersin City Training and Research Hospital, Mersin, Turkey.
Department of Infectious Diseases, Mersin City Training and Research Hospital, Mersin, Turkey.
Andrologia. 2021 Sep;53(8):e14145. doi: 10.1111/and.14145. Epub 2021 Jun 11.
The SARS-CoV-2 set off a pandemic involving millions of people around the world. The topic of discussion is the possible viral detection in different body fluids than respiratory droplets. Therefore, we evaluated the possible presence of SARS-CoV-2 in semen and urine samples. Thirty patients were included in the study aged 35.67 ± 6.84 years. The day after the pharyngeal and/or nose swab of SARS-CoV-2 was positive, urine and semen samples were taken from patients, and the presence of SARS-CoV-2 was investigated. Laboratory tests and chest CT findings were evaluated simultaneously. SARS-CoV-2 was detected in four (13.3%) patients' semen samples and in seven (23.3%) patients' urine samples. White blood cell (WBC), neutrophil, C-reactive protein (CRP), ferritin, alanine transaminase (ALT), lactate dehydrogenase (LDH) and procalcitonin were significantly higher in patients with SARS-CoV-2 in semen (p < .05), though no statistical difference was found in urine (p > .05). Patients with severe pneumonia findings in Chest CT images are likely to be PCR positive in semen and urine samples (p = .005, p = .001). SARS-CoV-2 was not detected in urine and semen samples of patients after they had recovered (average duration 23 ± 4 days). SARS-CoV-2 can be detected in the urogenıtal fluıds of patients with severe clinical conditions and high viral load.
SARS-CoV-2 引发了一场涉及全球数百万人的大流行。讨论的主题是在呼吸道飞沫以外的其他体液中可能检测到病毒。因此,我们评估了 SARS-CoV-2 在精液和尿液样本中的可能存在。研究纳入了 30 名年龄为 35.67±6.84 岁的患者。在咽拭子和/或鼻拭子 SARS-CoV-2 阳性后的第二天,从患者中采集尿液和精液样本,并检测 SARS-CoV-2 的存在。同时评估实验室检查和胸部 CT 结果。在 4 名(13.3%)患者的精液样本和 7 名(23.3%)患者的尿液样本中检测到 SARS-CoV-2。在精液中 SARS-CoV-2 阳性的患者中,白细胞(WBC)、中性粒细胞、C 反应蛋白(CRP)、铁蛋白、丙氨酸转氨酶(ALT)、乳酸脱氢酶(LDH)和降钙素原显著升高(p<0.05),而尿液中则无统计学差异(p>0.05)。在胸部 CT 图像中发现严重肺炎表现的患者,其精液和尿液样本 PCR 阳性的可能性更大(p=0.005,p=0.001)。在患者康复后(平均持续时间为 23±4 天)未在尿液和精液样本中检测到 SARS-CoV-2。在病毒载量高且临床症状严重的患者中,可以在其泌尿生殖道样本中检测到 SARS-CoV-2。