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2020 - 2021年南非医护人员中新冠病毒病的住院情况及死亡率

COVID-19 hospital admissions and mortality among healthcare workers in South Africa, 2020-2021.

作者信息

Tlotleng Nonhlanhla, Cohen Cheryl, Made Felix, Kootbodien Tahira, Masha Maureen, Naicker Nisha, Blumberg Lucille, Jassat Waasila

机构信息

Epidemiology and Surveillance Section, National Institute for Occupational Health, National Health Laboratory Service, Braamfontein, Johannesburg 2001, South Africa.

Environmental Health Department, Faculty of Health Sciences, University of Johannesburg, Johannesburg 2028, South Africa.

出版信息

IJID Reg. 2022 Dec;5:54-61. doi: 10.1016/j.ijregi.2022.08.014. Epub 2022 Sep 1.

Abstract

OBJECTIVES

This study describes the characteristics of admitted HCWs reported to the DATCOV surveillance system, and the factors associated with in-hospital mortality in South African HCWs.

METHODS

Data from March 5, 2020 to April 30, 2021 were obtained from DATCOV, a national hospital surveillance system monitoring COVID-19 admissions in South Africa. Characteristics of HCWs were compared with those of non-HCWs. Furthermore, a logistic regression model was used to assess factors associated with in-hospital mortality among HCWs.

RESULTS

In total, there were 169 678 confirmed COVID-19 admissions, of which 6364 (3.8%) were HCWs. More of these HCW admissions were accounted for in wave 1 (48.6%;  = 3095) than in wave 2 (32.0%;  = 2036). Admitted HCWs were less likely to be male (28.2%;  = 1791) (aOR 0.3; 95% CI 0.3-0.4), in the 50-59 age group (33.1%;  = 2103) (aOR 1.4; 95% CI 1.1-1.8), or accessing the private health sector (63.3%;  = 4030) (aOR 1.3; 95% CI 1.1-1.5). Age, comorbidities, race, wave, province, and sector were significant risk factors for COVID-19-related mortality.

CONCLUSION

The trends in cases showed a decline in HCW admissions in wave 2 compared with wave 1. Acquired SARS-COV-2 immunity from prior infection may have been a reason for reduced admissions and mortality of HCWs despite the more transmissible and more severe beta variant in wave 2.

摘要

目的

本研究描述了向DATCOV监测系统报告的住院医护人员的特征,以及与南非医护人员院内死亡相关的因素。

方法

数据来自DATCOV,这是一个监测南非COVID-19住院情况的全国性医院监测系统,时间范围为2020年3月5日至2021年4月30日。将医护人员的特征与非医护人员的特征进行比较。此外,使用逻辑回归模型评估与医护人员院内死亡相关的因素。

结果

总共有169678例确诊的COVID-19住院病例,其中6364例(3.8%)是医护人员。这些医护人员住院病例中,第一波(48.6%;n = 3095)比第二波(32.0%;n = 2036)更多。住院医护人员男性比例较低(28.2%;n = 1791)(调整后比值比[aOR]为0.3;95%置信区间[CI]为0.3 - 0.4),50 - 59岁年龄组比例较低(33.1%;n = 2103)(aOR为1.4;95% CI为1.1 - 1.8),或使用私立医疗部门服务的比例较低(63.3%;n = 4030)(aOR为1.3;95% CI为1.1 - 1.5)。年龄、合并症、种族、疫情波次、省份和医疗部门是与COVID-19相关死亡的显著风险因素。

结论

病例趋势显示,与第一波相比,第二波医护人员住院病例有所下降。尽管第二波中β变异株传播性更强、更严重,但既往感染获得的SARS-CoV-2免疫力可能是医护人员住院和死亡人数减少的一个原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1f2/9526135/721152a285a7/gr1.jpg

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