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对大鼠体内作为全身三碘甲状腺原氨酸产生部位的棕色脂肪组织进行直接评估。

Direct assessment of brown adipose tissue as a site of systemic tri-iodothyronine production in the rat.

作者信息

Fernandez J A, Mampel T, Villarroya F, Iglesias R

出版信息

Biochem J. 1987 Apr 1;243(1):281-4. doi: 10.1042/bj2430281.

Abstract

Tri-iodothyronine (T3)production by interscapular brown fat was studied by measurements of arterio-venous differences and blood flow across the tissue in rats exposed to the following situations: controls, acute cold, chronic cold and starvation. Results demonstrate that brown adipose tissue is a source of systemic T3 in the rat and that the T3 release is modulated according to the physiological situation of the animal: increased in cold exposure and inhibited in starvation.

摘要

通过测量处于以下几种情况的大鼠肩胛间棕色脂肪组织的动静脉差异和血流量,研究了三碘甲状腺原氨酸(T3)的产生情况:对照组、急性寒冷、慢性寒冷和饥饿状态。结果表明,棕色脂肪组织是大鼠体内全身性T3的一个来源,并且T3的释放根据动物的生理状态受到调节:在寒冷暴露时增加,在饥饿时受到抑制。

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