EPI-PHARE (French National Agency for Medicines and Health Products Safety, ANSM; and French National Health Insurance, CNAM), Saint-Denis Cedex, France.
University Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Anti-infective Evasion and Pharmacoepidemiology, Center for Research in Epidemiology and Population Health (CESP), Montigny le Bretonneux, France.
Int J Gynaecol Obstet. 2023 Feb;160(2):594-603. doi: 10.1002/ijgo.14438. Epub 2022 Sep 10.
To assess the user profiles of copper intrauterine devices (Cu-IUD) and levonorgestrel intrauterine systems (LNG-IUS) in France in 2019 and the rates of continuation 1 year later.
A population-based study was conducted of all French women aged 13-49 years for whom an IUD was dispensed in 2019. Information was collected from the French National Health Data System about their characteristics at the time of dispensation and indicators of continued use 1 year later. Associations between these characteristics and the type of IUD were analyzed using multivariate regressions.
A total of 477 705 Cu-IUDs and 355 242 LNG-IUSs (mean age 32.5 ± 7.3 and 36.4 ± 7.7 years, respectively) were dispensed in 2019. After adjustment, having a LNG-IUS rather than a Cu-IUD was associated with being aged 35-44 years compared to 25-35 years (odds ratio [OR ] 2.03, 95% confidence interval [CI] 2.01-2.05), having a prescription by a gynecologist rather than a general practitioner (OR 1.09, 95% CI 1.08-1.11), and having a gynecological history (OR 2.28, 95% CI 2.20-2.36). The continuation rates 1 year after dispensation were 86.4% for Cu-IUD versus 85.7% for LNG-IUS. A Cu-IUD dispensation rather than a LNG-IUS one was associated with a higher chance of continued use 1 year later.
Two different patterns of use of Cu-IUDs and LNG-IUSs in France are highlighted.
评估 2019 年法国铜宫内节育器（Cu-IUD）和左炔诺孕酮宫内节育系统（LNG-IUS）的用户特征，以及 1 年后的续用率。
对 2019 年所有在法国因宫内节育器而配药的 13-49 岁的法国女性进行基于人群的研究。从法国国家卫生数据系统收集了她们在配药时的特征以及 1 年后持续使用的指标。使用多变量回归分析了这些特征与宫内节育器类型之间的关联。
2019 年共配药 477705 个 Cu-IUD 和 355242 个 LNG-IUS（平均年龄分别为 32.5±7.3 和 36.4±7.7 岁）。调整后，与 25-35 岁相比，35-44 岁（比值比[OR] 2.03，95%置信区间[CI] 2.01-2.05）、由妇科医生而非全科医生开具处方（OR 1.09，95% CI 1.08-1.11）、有妇科病史（OR 2.28，95% CI 2.20-2.36）的患者更倾向于使用 LNG-IUS 而不是 Cu-IUD。1 年后的续用率分别为 Cu-IUD 86.4%和 LNG-IUS 85.7%。与 LNG-IUS 相比，Cu-IUD 配药更有可能在 1 年后继续使用。
突出了法国 Cu-IUD 和 LNG-IUS 使用的两种不同模式。
