Bossio R, Capei R, Marcaccini S, Pepino R, Tiscione E
Arzneimittelforschung. 1987 Apr;37(4):377-9. doi: 10.1002/chin.198734193.
A series of 1-benzyl-2-arylthio (or heteroarylthio)-5-imidazolecarbohydroxamic acids (Va-e) was prepared starting from the corresponding imidazole-5-carboxylic acids IIIa-e via acid chlorides IVa-e. Tests of biological activity showed that compounds Va-e are fairly active against Escherichia coli and Candida albicans.
从相应的咪唑-5-羧酸IIIa-e出发，经酰氯IVa-e制备了一系列1-苄基-2-芳硫基（或杂芳硫基）-5-咪唑碳羟肟酸（Va-e）。生物活性测试表明，化合物Va-e对大肠杆菌和白色念珠菌具有相当的活性。
