Laboratoire de Génie Enzymatique et Microbiologie, Équipe de Biotechnologie des Algues, Ecole Nationale d'Ingénieurs de Sfax, Université de Sfax, 3038 Sfax, Tunisia; Université Clermont Auvergne, CNRS, SIGMA Clermont, Institut Pascal, F-63000 Clermont-Ferrand, France.
Université de Lorraine, INRAE, Unité de Recherche Animal et Fonctionnalités des Produits Animaux (UR AFPA), USC 340, Nancy F-54000, France.
Int J Biol Macromol. 2022 Nov 30;221:1238-1250. doi: 10.1016/j.ijbiomac.2022.08.206. Epub 2022 Sep 5.
Due to the increase in industrial demand for new biosourced molecules (notably bioactive exopolysaccharides (EPS)), microalgae are gaining popularity because of their nutraceutical potential and benefits health. Such health effects are delivered by specific secondary metabolites, e.g., pigments, exopolysaccharides, polyunsaturated fatty acids, proteins, and glycolipids. These are suitable for the subsequent uses in cosmetic, nutraceutical, pharmaceutical, biofuels, biological waste treatment, animal feed and food fields. In this regard, a special focus has been given in this review to describe the various methods used for extraction and purification of polysaccharides. The second part of the review provides an up-to-date and comprehensive summary of parameters affecting the microalgae growth and insights to maximize the metabolic output by understanding the intricacies of algal development and polysaccharides production. In the ultimate part, the health and nutraceutical claims associated with marine algal bioactive polysaccharides, explaining their noticeable potential for biotechnological applications, are summarized and comprehensively discussed.
由于工业对新型生物源分子（尤其是生物活性胞外多糖 (EPS)）的需求不断增加，微藻因其具有营养潜力和健康益处而受到关注。这些健康影响是由特定的次级代谢物如色素、胞外多糖、多不饱和脂肪酸、蛋白质和糖脂等传递的。这些物质适用于随后在化妆品、营养保健品、制药、生物燃料、生物废物处理、动物饲料和食品领域的应用。在这方面，本综述特别关注描述各种用于提取和纯化多糖的方法。综述的第二部分提供了一个最新和全面的总结，概述了影响微藻生长的参数，并深入了解藻类发育和多糖生产的复杂性，以最大限度地提高代谢产物的产量。在最后一部分，总结并全面讨论了与海洋藻类生物活性多糖相关的健康和营养保健品的声称，解释了它们在生物技术应用方面的显著潜力。
