Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Institute of Applied Chemistry, Guizhou University, Guiyang, 550025, China.
Department of Chemistry, University of Hull, Hull, HU6 7RX, UK.
Anal Chim Acta. 2022 Sep 15;1226:340262. doi: 10.1016/j.aca.2022.340262. Epub 2022 Aug 19.
The efficient and selective detection of isomers is an attractive but challenging area. In this study, a supramolecular fluorescent probe based on cucurbit[8]uril (Q[8]) and a pyrene-based derivative (G) was prepared, which effectively recognized and removed o-nitrophenol (o-NP) from a mixture of nitrophenol isomers. The newly designed probe G@Q[8] was characterized by NMR spectroscopy, fluorescence emission and UV-Vis spectroscopy, and its host-guest properties in aqueous solution were investigated. The results revealed that the system forms a stable inclusion complex with a stoichiometric ratio of 1:1, which was accompanied by a distinct fluorescence enhancement of G. Moreover, it was employed for the rapid detection of nitrophenol isomers where o-NP showed a dramatical quenching efficiency with a detection limit of 1.53 × 10 mol·L. This highly efficient supramolecular fluorescent probe offers a new strategy for the convenient detection and removal of o-NP from mixtures in aqueous medium.
对异构体的高效选择性检测是一个具有吸引力但极具挑战性的领域。在本研究中，制备了一种基于葫芦[8]脲（Q[8]）和基于芘的衍生物（G）的超分子荧光探针，该探针可有效识别并从硝基酚异构体混合物中去除邻硝基苯酚（o-NP）。新设计的探针 G@Q[8]通过 NMR 光谱、荧光发射和紫外可见光谱进行了表征，并研究了其在水溶液中的主客体性质。结果表明，该体系形成了具有 1:1 化学计量比的稳定包合物，同时伴随着 G 的明显荧光增强。此外，该体系还可用于快速检测硝基酚异构体，其中邻硝基苯酚表现出显著的猝灭效率，检测限为 1.53×10 mol·L。这种高效的超分子荧光探针为在水介质中从混合物中方便地检测和去除邻硝基苯酚提供了一种新策略。
