ENNOVA Institute of Life Science and Technology, ENN Group, Langfang 065001, China.
Quantum Biology Research Lab, PO Box 1402, Ridgway, CO, USA.
Explore (NY). 2023 Mar-Apr;19(2):223-227. doi: 10.1016/j.explore.2022.08.003. Epub 2022 Aug 6.
Written words demonstrated specific effects on biochemical measures and cell growth in cultured mammalian cells in previous study. We examined the protection and reparative effects of Chinese texts with positive meaning and the word "Buddha" on oxidative-damaged cells, with the goal of exploring the therapeutic effect of such characters.
The human embryonic kidney cell line HEK293T was utilized, with the oxidative- damaged cell model produced by hydrogen peroxide (HO). Double-blind experiments were set up to ensure all operators involved in the experiments did not know the contents of the texts in envelopes. Petri-dishes (9 plates) containing oxidative-damaged cells were selected randomly for three controls, three treatments by texts with positive meaning, and another three treatment by the word "Buddha". Cells were sub-sampled at 3 h and 24 h to examine growth and mitochondrial functions. All data are expressed relative to the controls.
Compared with the control group, mitochondrial functions were enhanced as evidenced by increased adenosine triphosphate (ATP) levels, accompanied by the significant improvement in cell growth rate for the groups treated by positive texts and the word "Buddha". Reactive oxygen species (ROS) levels were decreased significantly in positive texts treatment, which suggested that the antioxidant capacity of cells was also improved.
This study revealed that certain texts can potentially offer protection and accelerate the cellular repair for oxidative-damaged cells.
在之前的研究中，书面文字对培养的哺乳动物细胞的生化指标和细胞生长表现出了特定的影响。我们检验了具有积极意义的中文文本和“佛”字对氧化损伤细胞的保护和修复作用，旨在探索这些字符的治疗效果。
使用人胚肾细胞系 HEK293T，通过过氧化氢（HO）产生氧化损伤细胞模型。设置双盲实验以确保所有参与实验的操作人员均不知道信封中文本的内容。随机选择含有氧化损伤细胞的 9 个培养皿（9 个培养皿）进行三组对照、三组具有积极意义的文本处理和三组“佛”字处理。在 3 h 和 24 h 时进行细胞亚采样，以检查细胞的生长和线粒体功能。所有数据均表示为与对照组相比的相对值。
与对照组相比，通过增加三磷酸腺苷（ATP）水平，证明线粒体功能得到增强，同时具有积极意义的文本和“佛”字处理组的细胞生长速率也显著提高。阳性文本处理组的活性氧（ROS）水平显著降低，表明细胞的抗氧化能力也得到了提高。
本研究表明，某些文本可能为氧化损伤细胞提供保护并加速细胞修复。
