Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council (CNR), Via G. Amendola 122/O, 70126 Bari, Italy.
Int J Mol Sci. 2024 Jun 21;25(13):6841. doi: 10.3390/ijms25136841.
Vibration and sound are the shaping matrix of the entire universe. Everything in nature is shaped by energy vibrating and communicating through its own sound trail. Every cell within our body vibrates at defined frequencies, generating its peculiar "sound signature". Mitochondria are dynamic, energy-transforming, biosynthetic, and signaling organelles that actively transduce biological information. Novel research has shown that the mitochondrial function of mammalian cells can be modulated by various energetic stimuli, including sound vibrations. Regarding acoustic vibrations, definite types of music have been reported to produce beneficial impacts on human health. In very recent studies, the effects of different sound stimuli and musical styles on cellular function and mitochondrial activity were evaluated and compared in human cells cultured in vitro, investigating the underlying responsible molecular mechanisms. This narrative review will take a multilevel trip from macro to intracellular microenvironment, discussing the intimate vibrational sound activities shaping living matter, delving deeper into the molecular mechanisms underlying the sound modulation of biological systems, and mainly focusing our discussion on novel evidence showing the competence of mitochondria in acting as energy portals capable of sensing and transducing the subtle informational biofields of sound vibration.
振动和声音是整个宇宙的塑造矩阵。自然界中的一切都是由振动的能量通过自身的声音轨迹进行沟通和塑造的。我们体内的每一个细胞都以特定的频率振动，产生其独特的“声音特征”。线粒体是具有活力的、能量转换的、生物合成的和信号传导的细胞器，能够主动传递生物信息。新的研究表明，哺乳动物细胞的线粒体功能可以通过各种能量刺激来调节，包括声音振动。关于声振动，已经有报道称某些类型的音乐对人类健康产生有益影响。在最近的研究中，评估和比较了不同声音刺激和音乐风格对体外培养的人类细胞的细胞功能和线粒体活性的影响，研究了潜在的负责分子机制。这篇综述将从宏观到细胞内微环境进行多层次的探讨，讨论塑造生命物质的微观振动声音活动，深入探讨生物系统声音调节的分子机制，并主要关注显示线粒体作为能够感知和传递声音振动微妙信息生物场的能量门户的能力的新证据。
