Shao Y H, Jiang L B
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.
Zhonghua Yan Ke Za Zhi. 2022 Sep 11;58(9):731-735. doi: 10.3760/cma.j.cn112142-20210907-00415.
Optical coherence tomography angiography (OCTA) is a new vascular imaging technology based on high-resolution optical coherence tomography image analysis. It can scan the moving red blood cells in blood vessels for three-dimensional imaging of human retinal and choroidal vessels. Since the close connection of vascular endothelial cells of the blood-retinal barrier is similar to that of the blood-brain barrier, the role of OCTA in the research of pathogenesis and course monitoring of a variety of central system diseases such as Alzheimer's disease, Parkinson's disease, stroke, migraine, multiple sclerosis and optic neuromyelitis has been widely discussed. This article reviews the application and progress of OCTA in central nervous system diseases.
光学相干断层扫描血管造影（OCTA）是一种基于高分辨率光学相干断层扫描图像分析的新型血管成像技术。它可以扫描血管中移动的红细胞，对人体视网膜和脉络膜血管进行三维成像。由于血视网膜屏障的血管内皮细胞紧密连接与血脑屏障相似，OCTA在阿尔茨海默病、帕金森病、中风、偏头痛、多发性硬化症和视神经脊髓炎等多种中枢系统疾病的发病机制研究和病程监测中的作用已得到广泛讨论。本文综述了OCTA在中枢神经系统疾病中的应用及进展。
