Ophthalmology Department, Railway Hospital, Katowice Panewnicka 65, 40765, Katowice, Poland.
II School of Medicine with the Division of Dentistry, Zabrze Medical University of Silesia, Katowice, Poland.
Curr Neurol Neurosci Rep. 2018 Oct 18;18(12):96. doi: 10.1007/s11910-018-0911-x.
The article reviews the recent findings on the use of optical coherence tomography angiography (OCTA) in neurology.
OCTA is a new addition to the powerful and complementary technology of the OCT. Due to its noninvasiveness, and reproducibility, it is possible to obtain high-resolution 3D images of the vessels of the human eye. As the vessels of the retina with the presence of endothelial cell's tight junctions resemble the brain vessels, it was hypothesized that the imaging of the retinal vessels might bring insight into brain vessels. OCTA has been effectively used to predict retinal vessel abnormalities in dementia, demyelization, optic disc neuropathies, and inherited degenerative diseases. Most common findings were decrease of vascular density and flow and an increase of avascular zones. Although OCTA is a relative new technology, recent studies show that it can be successfully applied in neurology.
本文综述了光学相干断层扫描血管造影（OCTA）在神经病学中的最新应用研究进展。
OCTA 是 OCT 强大互补技术的新成员。由于其非侵入性和可重复性，可以获得人眼血管的高分辨率 3D 图像。由于视网膜血管内皮细胞紧密连接的存在类似于脑内血管，因此推测视网膜血管的成像可能有助于了解脑内血管。OCTA 已被有效地用于预测痴呆、脱髓鞘、视盘神经病和遗传性退行性疾病中的视网膜血管异常。最常见的发现是血管密度和血流减少，以及无血管区增加。虽然 OCTA 是一项相对较新的技术，但最近的研究表明，它可以成功地应用于神经病学。
