[Optical coherence tomography angiography in neuronal diseases : Preliminary findings].

BACKGROUND

Optical coherence tomography angiography (OCTA) enables a noninvasive detailed imaging of retinal and choroidal vessels of the fundus. In neuronal diseases changes in retinal structures can be imaged and measured with OCT and OCTA.

OBJECTIVE

Can OCTA be used in neuronal diseases?

MATERIAL AND METHODS

Evaluation of recent scientific articles and studies extracted from Medline on the topic of OCTA and neuronal diseases.

RESULTS

It could be shown that Alzheimer type dementia, Parkinson's disease, multiple sclerosis. cerebral infarction and CADASIL are neuronal diseases with rarification of retinal vessels and atrophy of the retinal layers in the ocular fundus.

CONCLUSION

These findings are beyond all changes which can be appreciated with ophthalmoscopy and OCTA parameters could serve in the future as supplementary biomarkers for assessment of the retinal-neurovascular coupling in these diseases.